Role of endogenous adenosine as a modulator of syncope induced during tilt testing

AY Saadjian, S Lévy, F Franceschi, I Zouher… - Circulation, 2002 - Am Heart Assoc
Background— Previous reports that used head-up tilt testing and adenosine administration
have suggested that adenosine may be an important endogenous mediator that may trigger …

Hemodynamic effects of bilevel nasal positive airway pressure ventilation in patients with heart failure

FF Philip-Joët, FF Paganelli, HL Dutau, AY Saadjian - Respiration, 1999 - karger.com
Aims: Benefits of nasal continuous positive airway pressure (CPAP) in patients presenting
with chronic heart failure (CHF) are controversial. The purpose of this study was to compare …

Head-up tilt induced syncope and adenosine A2A receptor gene polymorphism

AY Saadjian, V Gerolami, R Giorgi… - European heart …, 2009 - academic.oup.com
Aims High adenosine plasma levels and high expression of adenosine A 2A receptors are
observed in patients with unexplained syncope and a positive head-up tilt test (HUT). This …

Adenosine plasma concentration in pulmonary hypertension

AY Saadjian, F Paganelli… - Cardiovascular …, 1999 - academic.oup.com
Objective: In this study, we sought to appreciate the role of adenosine in the regulation of
pulmonary vascular tone, especially in the case of clinical pulmonary hypertension, by …

Long-term treatment of chronic obstructive lung disease by nifedipine: an 18-month haemodynamic study

AY Saadjian, FF Philip-Joet, R Vestri… - European Respiratory …, 1988 - Eur Respiratory Soc
This long-term controlled study was undertaken to assess the haemodynamic effects of chronic
administration of Nifedipine (N). Twenty patients suffering from pulmonary hypertension …

Increased expression of adenosine A2A receptors in patients with spontaneous and head-up-tilt-induced syncope

L Carrega, AY Saadjian, L Mercier, I Zouher… - Heart Rhythm, 2007 - Elsevier
BACKGROUND: Adenosine may play a role in the triggering of neurocardiogenic syncope,
but no information on adenosine receptors is available at the present time. OBJECTIVE: The …

Plasma beta-endorphin and adenosine concentration in pulmonary hypertension

AY Saadjian, F Paganelli, MA Juin, C Devaux… - The American journal of …, 2000 - Elsevier
To determine whether β-endorphin plays a role in the regulation of pulmonary vascular tone
in patients with pulmonary hypertension, we investigated the relations between …

Effect of almitrine bismesylate on pulmonary vasoreactivity to hypoxia in chronic obstructive pulmonary disease

AY Saadjian, FF Philip-Joel, A Barret… - European …, 1994 - Eur Respiratory Soc
The aim of this double-blind, placebo-controlled study was to determine whether acute
administration of almitrine enhances hypoxic pulmonary vasoconstriction in patients with chronic …

Hemodynamic and oxygen delivery responses to nifedipine in pulmonary hypertension secondary to chronic obstructive lung disease

AY Saadjian, F Philip-Joet, A Arnaud - Cardiology, 1987 - karger.com
The effects of a single dose of nifedipine (20 mg sublingually) on hemodynamics and tissue
oxygenation were evaluated in 24 patients suffering from pulmonary hypertension …

Increased Expression of Adenosine A2A Receptors in Patients with Spontaneous and Head-Up Tilt Induced Syncope

S Levy, L Carrega, AY Saadjian, P Sbragia, F Paganelli… - 2006 - Am Heart Assoc
Background - Recent studies have suggested that adenosine may be an endogenous
mediator in susceptible patients with vasovagal syncope. Adenosine receptors expression is …