User profiles for AA Sahin

Aysegul Sahin

MD Anderson Cancer Center
Verified email at mdanderson.org
Cited by 51511

[PDF][PDF] Benign breast diseases: classification, diagnosis, and management

M Guray, AA Sahin - The oncologist, 2006 - Wiley Online Library
… Correspondence: Aysegul Sahin, MD, University of Texas MD Anderson Cancer Center,
Unit 85, 1515 Holcombe Boulevard, Houston, Texas 77030, USA. Telephone: 713-794-1500; …

Carcinoma of the male breast

IA Jaiyesimi, AU Buzdar, AA Sahin… - Annals of internal …, 1992 - acpjournals.org
▪ The natural history and current management of carcinoma of the breast in men is reviewed.
Articles published from 1942 to 1992 on the natural history, clinical manifestations, …

Neoadjuvant chemotherapy for breast carcinoma: multidisciplinary considerations of benefits and risks

…, KK Hunt, GJ Whitman, AA Sahin… - … Journal of the …, 2003 - Wiley Online Library
BACKGROUND The majority of patients with breast carcinoma receive chemotherapy as a
component of multimodality treatment. Over the past decade, it has become increasingly …

[HTML][HTML] PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients

Y Nagata, KH Lan, X Zhou, M Tan, FJ Esteva, AA Sahin… - Cancer cell, 2004 - cell.com
The ErbB2-targeting antibody, trastuzumab (Herceptin), has remarkable therapeutic efficacy
in certain patients with ErbB2-overexpressing tumors. The overall trastuzumab response rate…

Significantly higher pathologic complete remission rate after neoadjuvant therapy with trastuzumab, paclitaxel, and epirubicin chemotherapy: results of a randomized …

…, TL Smith, KK Hunt, SE Singletary, AA Sahin… - Journal of clinical …, 2005 - ascopubs.org
Purpose The objective of this study was to determine whether the addition of trastuzumab to
chemotherapy in the neoadjuvant setting could increase pathologic complete response (…

Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth

…, D Palmieri, J Saunus, S Lakhani, S Huang, AA Sahin… - Nature, 2015 - nature.com
The development of life-threatening cancer metastases at distant organs requires
disseminated tumour cells’ adaptation to, and co-evolution with, the drastically different …

[HTML][HTML] Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity

…, Y Wang, J Yao, CC Lee, HJ Wu, AA Sahin… - Nature …, 2016 - nature.com
Extracellular interaction between programmed death ligand-1 (PD-L1) and programmed cell
death protein-1 (PD-1) leads to tumour-associated immune escape. Here we show that the …

[HTML][HTML] IKKβ suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway

…, JY Hung, CC Lai, Q Ding, JL Su, JY Yang, AA Sahin… - Cell, 2007 - cell.com
TNFα has recently emerged as a regulator linking inflammation to cancer pathogenesis, but
the detailed cellular and molecular mechanisms underlying this link remain to be elucidated. …

ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

…, KJ Chang, CD Hsiao, FJ Tsai, CH Tsai, AA Sahin… - Nature cell …, 2008 - nature.com
The RAS–ERK pathway is known to play a pivotal role in differentiation, proliferation and
tumour progression. Here, we show that Erk downregulates Forkhead box O 3a (FOXO3a) by …

[PDF][PDF] Deubiquitination and stabilization of PD-L1 by CSN5

…, Q Ding, Y Wang, Y Yang, CH Chen, AA Sahin… - Cancer cell, 2016 - cell.com
Pro-inflammatory cytokines produced in the tumor microenvironment lead to eradication of
anti-tumor immunity and enhanced tumor cell survival. In the current study, we identified …