Positron emission particle tracking has been used to track the motion of a single radioactively
labelled tracer particle within a bed of similar particles in a partially filled horizontal rotating …

Background Emphysema and small airway disease both contribute to chronic obstructive
pulmonary disease (COPD), a disease characterised by accelerated decline in lung function. …

Background Increased airway wall thickness (AWT) and parenchymal lung destruction
bothcontribute to airflow limitation. Advances in computed tomography (CT)post-processing …

OBJECTIVE. In lung cancer screening, the prevalence of chronic respiratory symptoms is high
among heavy smokers. The purpose of this study was to compare CT-derived airway wall …

Rationale: Airway wall thickness (AWT) is affected by both environmental and genetic
factors and is strongly associated with airflow limitation in smaller airways. Objectives: To …

Rationale We have previously shown increased expression of the Frizzled-8 receptor of the
Wingless/integrase-1 (WNT) signalling pathway in COPD. Here, we investigated if the …

Background Chronic mucus hypersecretion (CMH) is associated with an increased frequency
of respiratory infections, excess lung function decline, and increased hospitalisation and …

Smoking is a notorious risk factor for chronic mucus hypersecretion (CMH). CMH frequently
occurs in chronic obstructive pulmonary disease (COPD). The question arises whether the …

Background Chronic mucus hypersecretion (CMH) is highly prevalent in smokers and associated
with an accelerated lung function decline and chronic obstructive pulmonary disease (…

Background Guidelines on COVID-19 management are developed as we learn from this
pandemic. However, most research has been done on hospitalised patients and the impact of …