BACKGROUND: A better understanding of the environmental factors leading to inflammatory
bowel disease should help to prevent occurrence of the disease and its relapses. AIM: To …

Objective: This paper describes the ad hoc methodological concepts and procedures
developed to improve the comparability of Nutrient databases (NDBs) across the 10 European …

Background Previous studies have relied predominantly on the body-mass index (BMI, the
weight in kilograms divided by the square of the height in meters) to assess the association of …

The European Prospective Investigation into Cancer and Nutrition (EPIC) is an ongoing
multi-centre prospective cohort study designed to investigate the relationship between nutrition …

Background Ambient air pollution is suspected to cause lung cancer. We aimed to assess
the association between long-term exposure to ambient air pollution and lung cancer …

Background: Current evidence suggests that high red meat intake is associated with increased
colorectal cancer risk. High fish intake may be associated with a decreased risk, but the …

Background Low-risk limits recommended for alcohol consumption vary substantially across
different national guidelines. To define thresholds associated with lowest risk for all-cause …

Objective To use the rs1229984 variant in the alcohol dehydrogenase 1B gene (ADH1B) as
an instrument to investigate the causal role of alcohol in cardiovascular disease. Design …

In an analysis of 31,717 cancer cases and 26,136 cancer-free controls from 13 genome-wide
association studies, we observed large chromosomal abnormalities in a subset of clones in …

The evidence for anthropometric factors influencing breast cancer risk is accumulating, but
uncertainties remain concerning the role of fat distribution and potential effect modifiers. We …