Near‐infrared (NIR) spectroscopy can potentially provide on‐line information on substrate,
biomass, product, and metabolite concentrations in fermentation processes, which could be …

Covering: 1995 to 2006 The synthesis of secondary metabolites by microorganisms,
specifically antibiotics, is of great scientific and economic importance. The onset (control and …

With the continuous development, in the last decades, of analytical techniques providing
complex information at single cell level, the study of cell heterogeneity has been the focus of …

An insufficient surgical workforce is a major barrier to safe surgical care for billions of people
worldwide. 1 Although a critical shortage of a spectrum of surgical providers has been …

The uncertainty and sensitivity analysis are evaluated for their usefulness as part of the
model‐building within Process Analytical Technology applications. A mechanistic model …

Background Omalizumab is an established anti-IgE therapy for the treatment of allergic
diseases that prevents IgE from binding to its receptor. QGE031 is an investigational anti-IgE …

Background Asthma is a heterogeneous disease in which there is a differential response to
asthma treatments. This heterogeneity needs to be evaluated so that a personalized …

Background A common side effect following radical prostatectomy is urinary incontinence.
Here, we describe a novel surgical technique to reduce postoperative urinary incontinence …

Forest inventories throughout the world have evolved gradually over time. The content as
well as the concepts and definitions employed are constantly adapted to the users’ needs. …

Mechanistic models are based on deterministic principles, and recently, interest in them has
grown substantially. Herein we present an overview of mechanistic models and their …