User profiles for A. Gazdhar

amiq gazdhar

University Hospital Bern, university of Bern
Verified email at unibe.ch
Cited by 1791

[HTML][HTML] Non-viral gene delivery methods for bone and joints

…, AI Salazar-Puerta, AS Croft, A Gazdhar… - … in Bioengineering and …, 2020 - frontiersin.org
Viral carrier transport efficiency of gene delivery is high, depending on the type of vector.
However, viral delivery poses significant safety concerns such as inefficient/unpredictable …

Alveolar derecruitment and collapse induration as crucial mechanisms in lung injury and fibrosis

D Lutz, A Gazdhar, E Lopez-Rodriguez… - American journal of …, 2015 - atsjournals.org
Idiopathic pulmonary fibrosis (IPF) and bleomycin-induced pulmonary fibrosis are associated
with surfactant system dysfunction, alveolar collapse (derecruitment), and collapse …

The Notch signaling pathway is related to neurovascular progression of pancreatic cancer

P Büchler, A Gazdhar, M Schubert, N Giese… - Annals of …, 2005 - journals.lww.com
Objective: To analyze the potential role of the Notch signaling pathway in pancreatic cancer
angiogenesis and invasion. Background: Angiogenesis, pain, and early neuroinvasion are …

[HTML][HTML] The secretome of induced pluripotent stem cells reduces lung fibrosis in part by hepatocyte growth factor

A Gazdhar, I Grad, L Tamò, M Gugger, A Feki… - Stem cell research & …, 2014 - Springer
Introduction Idiopathic pulmonary fibrosis (IPF) is a progressive and irreversible fibrotic lung
disease, resulting in respiratory insufficiency and reduced survival. Pulmonary fibrosis is a …

Cellular responses after exposure of lung cell cultures to secondary organic aerosol particles

…, M Kalberer, M Savi, T Geiser, A Gazdhar… - … science & technology, 2010 - ACS Publications
The scope of this work was to examine in vitro responses of lung cells to secondary organic
aerosol (SOA) particles, under realistic ambient air and physiological conditions occurring …

Gene transfer of hepatocyte growth factor by electroporation reduces bleomycin-induced lung fibrosis

A Gazdhar, P Fachinger, C van Leer… - … of Physiology-Lung …, 2007 - journals.physiology.org
Abnormal alveolar wound repair contributes to the development of pulmonary fibrosis after
lung injury. Hepatocyte growth factor (HGF) is a potent mitogenic factor for alveolar epithelial …

[HTML][HTML] HGF expressing stem cells in usual interstitial pneumonia originate from the bone marrow and are antifibrotic

A Gazdhar, N Susuri, K Hostettler, M Gugger… - PloS one, 2013 - journals.plos.org
Background Pulmonary fibrosis may result from abnormal alveolar wound repair after injury.
Hepatocyte growth factor (HGF) improves alveolar epithelial wound repair in the lung. Stem …

Generation of an alveolar epithelial type II cell line from induced pluripotent stem cells

…, H Abriel, L Knudsen, A Gazdhar… - … of Physiology-Lung …, 2018 - journals.physiology.org
Differentiation of primary alveolar type II epithelial cells (AEC II) to AEC type I in culture is a
major barrier in the study of the alveolar epithelium in vitro. The establishment of an AEC II …

Size-dependent accumulation of particles in lysosomes modulates dendritic cell function through impaired antigen degradation

…, IM Nita, S Balog, A Gazdhar… - International journal …, 2014 - Taylor & Francis
Introduction Nanosized particles may enable therapeutic modulation of immune responses
by targeting dendritic cell (DC) networks in accessible organs such as the lung. To date, …

[HTML][HTML] Mitochondrial DNA mutations and respiratory chain dysfunction in idiopathic and connective tissue disease-related lung fibrosis

…, AG Nicholson, A Wells, H Bhayani, A Gazdhar… - Scientific reports, 2019 - nature.com
Reactive oxygen species (ROS) are implicated in the aetiology of interstitial lung disease (ILD).
We investigated the role of large-scale somatically acquired mutations in mitochondrial …