User profiles for A. G. Rothfuchs

Antonio Rothfuchs

Karolinska Institutet
Verified email at ki.se
Cited by 4337

[HTML][HTML] Massive and rapid COVID-19 testing is feasible by extraction-free SARS-CoV-2 RT-PCR

…, H Safari, S Muradrasoli, AG Rothfuchs… - Nature …, 2020 - nature.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), is commonly diagnosed by reverse transcription polymerase chain …

Neutrophil secretion products pave the way for inflammatory monocytes

…, A Zernecke, EE Eriksson, AG Rothfuchs… - Blood, The Journal …, 2008 - ashpublications.org
The leukocyte response in inflammation is characterized by an initial recruitment of
polymorphonuclear leukocytes (PMN) preceding a second wave of monocytes to the site of injury or …

[HTML][HTML] Macrophage and T cell dynamics during the development and disintegration of mycobacterial granulomas

JG Egen, AG Rothfuchs, CG Feng, N Winter, A Sher… - Immunity, 2008 - cell.com
Granulomas play a key role in host protection against mycobacterial pathogens, with their
breakdown contributing to exacerbated disease. To better understand the initiation and …

[HTML][HTML] Intranasal Poly-IC treatment exacerbates tuberculosis in mice through the pulmonary recruitment of a pathogen-permissive monocyte/macrophage population

LRV Antonelli, AG Rothfuchs… - The Journal of …, 2010 - Am Soc Clin Investig
Type I IFN has been demonstrated to have major regulatory effects on the outcome of
bacterial infections. To assess the effects of exogenously induced type I IFN on the outcome of …

NK cell-derived IFN-γ differentially regulates innate resistance and neutrophil response in T cell-deficient hosts infected with Mycobacterium tuberculosis

CG Feng, M Kaviratne, AG Rothfuchs… - The Journal of …, 2006 - journals.aai.org
Although it is known that IFN-γ-secreting T cells are critical for control of Mycobacterium
tuberculosis infection, the contribution of IFN-γ produced by NK cells to host resistance to the …

[PDF][PDF] Intravital imaging reveals limited antigen presentation and T cell effector function in mycobacterial granulomas

JG Egen, AG Rothfuchs, CG Feng, MA Horwitz, A Sher… - Immunity, 2011 - cell.com
Cell-mediated adaptive immunity is critical for host defense, but little is known about T cell
behavior during delivery of effector function. Here we investigate relationships among antigen …

Dectin-1 interaction with Mycobacterium tuberculosis leads to enhanced IL-12p40 production by splenic dendritic cells

AG Rothfuchs, A Bafica, CG Feng, JG Egen… - The Journal of …, 2007 - journals.aai.org
Dectin-1 is a fungal pattern recognition receptor that binds to β-glucans and triggers cytokine
production by facilitating interaction with TLR2 or by directly activating spleen tyrosine …

Helicobacter hepaticus-Induced Colitis in Interleukin-10-Deficient Mice: Cytokine Requirements for the Induction and Maintenance of Intestinal Inflammation

MC Kullberg, AG Rothfuchs, D Jankovic… - Infection and …, 2001 - Am Soc Microbiol
We have previously shown that specific-pathogen-free interleukin-10 (IL-10)-deficient (IL-10
KO) mice reconstituted withHelicobacter hepaticus develop severe colitis associated with a …

Neutrophil degranulation mediates severe lung damage triggered by streptococcal M1 protein

O Soehnlein, S Oehmcke, AG Rothfuchs… - European …, 2008 - Eur Respiratory Soc
Streptococcus pyogenes of the M1 serotype can cause streptococcal toxic shock syndrome
commonly associated with acute lung injury. The aim of the present study was to investigate …

[HTML][HTML] SARS-CoV-2 promotes microglial synapse elimination in human brain organoids

…, SD Sheridan, RH Perlis, AG Rothfuchs… - Molecular …, 2022 - nature.com
Neuropsychiatric manifestations are common in both the acute and post-acute phase of
SARS-CoV-2 infection, but the mechanisms of these effects are unknown. In a newly established …