Alterations of the nitric oxide receptor, soluble guanylate cyclase (sGC) may contribute to
the pathophysiology of pulmonary arterial hypertension (PAH). In the present study, the …

Introduction: Head and neck squamous cell carcinoma (HNSCC) is one of the ten most common
cancer types worldwide - ranked on the sixth position with 560,000 new diagnoses and …

Introduction: Pancreatic ductal adenocarcinomas are one of the deadliest cancer types with
limited response to current therapies. Thus, this study examined changes in the proteome of …

The quality of an angiogram is determined to a great extent by the size of the patient, the
radiographic technique, the flow rate in the vascular system to be examined and the amount of …

In technique for lower extremity phlebography the patient is in a semi-upright position,
supporting his weight on the contralateral foot. The dye injection is made into a dorsal pedal vein …

Soluble guanylate cyclase (sGC), a key enzyme of the nitric oxide (NO) signaling pathway,
is attracting rapidly growing interest as a therapeutic target in cardiopulmonary disease, with …

… Dingendorf W … Dingendorf W, Swart B, Haberich H …

Nitric oxide is an endogenous pulmonary vasodilator that is synthesized from L-arginine in
pulmonary vascular endothelial cells by nitric oxide synthase and diffuses to adjacent …

… Dingendorf W …

It is now well established that the NO-sGC-cGMP signal transduction system mediates many
different physiological functions in almost every conceivable organ system; this has been …