Novel 2-benzylthio-5-(1, 3, 4-oxadiazol-2-yl) benzenesulfonamides with anticancer activity: Synthesis, QSAR study, and metabolic stability
J Sławiński, K Szafrański, A Pogorzelska… - European Journal of …, 2017 - Elsevier
A series of novel 2-benzylthio-4-chloro-5-(5-substituted 1,3,4-oxadiazol-2-yl)benzenesulfonamides
(4–27) have been synthesized as potential anticancer agents. MTT assay was …
(4–27) have been synthesized as potential anticancer agents. MTT assay was …
Characterization of a novel 21-kb deletion, CFTRdele2,3(21 kb), in the CFTR gene: a cystic fibrosis mutation of Slavic origin common in Central and East Europe
…, T Ivaschenko, V Baranov, M Witt, A Pogorzelski… - Human genetics, 2000 - Springer
We report a large genomic deletion of the cystic fibrosis transmembrane conductance regulator
(CFTR) gene, viz., a deletion that is frequently observed in Central and Eastern Europe. …
(CFTR) gene, viz., a deletion that is frequently observed in Central and Eastern Europe. …
RPGR mutations might cause reduced orientation of respiratory cilia
…, J Rutland, L Morgan, A Pogorzelski… - Pediatric …, 2013 - Wiley Online Library
RPGR gene encodes retinitis pigmentosa guanosine triphosphatase regulator protein,
mutations of which cause 70% of the X‐linked retinitis pigmentosa (XLRP) cases. Rarely, RPGR …
mutations of which cause 70% of the X‐linked retinitis pigmentosa (XLRP) cases. Rarely, RPGR …
Normal values for maximal static inspiratory and expiratory pressures in healthy children
W Tomalak, A Pogorzelski, J Prusak - Pediatric pulmonology, 2002 - Wiley Online Library
Maximal static respiratory pressures are a simple measure of respiratory muscle strength. In
order to construct a set of equations describing normal values, we measured maximal …
order to construct a set of equations describing normal values, we measured maximal …
[HTML][HTML] Mutations in radial spoke head genes and ultrastructural cilia defects in East-European cohort of primary ciliary dyskinesia patients
…, K Voelkel, B Klimek, H Dmeńska, A Pogorzelski… - PLoS …, 2012 - journals.plos.org
Primary ciliary dyskinesia (PCD) is a rare (1/20,000), multisystem disease with a complex
phenotype caused by the impaired motility of cilia/flagella, usually related to ultrastructural …
phenotype caused by the impaired motility of cilia/flagella, usually related to ultrastructural …
Safety and efficacy of the epithelial sodium channel blocker idrevloride in people with primary ciliary dyskinesia (CLEAN-PCD): a multinational, phase 2, randomised …
…, CE Milla, A O'Donnell, I Pink, A Pogorzelski… - The Lancet …, 2024 - thelancet.com
Background Mucociliary clearance is dysfunctional in people with primary ciliary dyskinesia,
resulting in the accumulation of dehydrated mucus in the airways that is difficult to clear. We …
resulting in the accumulation of dehydrated mucus in the airways that is difficult to clear. We …
[CITATION][C] Cystic fibrosis is a risk factor for celiac disease.
…, A Lisowska, B Oralewska, A Pogorzelski… - Acta Biochimica …, 2010 - ojs.ptbioch.edu.pl
The coexistence of cystic fibrosis (CF) and celiac disease (CD) has been reported. To our
knowledge there is no study directly comparing the incidence of CD in CF patients to that in the …
knowledge there is no study directly comparing the incidence of CD in CF patients to that in the …
[HTML][HTML] Fecal elastase-1 cut-off levels in the assessment of exocrine pancreatic function in cystic fibrosis
…, K Strzykala, M Kouniou, A Pogorzelski… - Journal of Cystic …, 2002 - Elsevier
Background: Fecal elastase-1 (E1) test is a sensitive and specific indirect test. However, there
are few data on the best cut-off level in the assessment of exocrine pancreatic function in …
are few data on the best cut-off level in the assessment of exocrine pancreatic function in …
Small intestine bacterial overgrowth does not correspond to intestinal inflammation in cystic fibrosis
A Lisowska, E Mądry, A Pogorzelski… - … journal of clinical and …, 2010 - Taylor & Francis
Introduction. Small intestine bacterial overgrowth (SIBO) has been reported in cystic fibrosis
(CF) patients. However, the potential link to intestinal inflammation has not been studied so …
(CF) patients. However, the potential link to intestinal inflammation has not been studied so …
Truncating mutations in exons 20 and 21 of OFD1 can cause primary ciliary dyskinesia without associated syndromic symptoms
…, A Rabiasz, M Dabrowski, A Pogorzelski… - Journal of medical …, 2019 - jmg.bmj.com
Background Primary ciliary dyskinesia (PCD) is a motile ciliopathy, whose symptoms include
airway infections, male infertility and situs inversus. Apart from the typical forms of PCD, …
airway infections, male infertility and situs inversus. Apart from the typical forms of PCD, …