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Page 1
Geranylgeranylacetone reduces cardiomyocyte stiffness and attenuates diastolic dysfunction in a rat model of cardiometabolic syndrome.
Waddingham MT, Sequeira V, Kuster DWD, Dal Canto E, Handoko ML, de Man FS, da Silva Gonçalves Bós D, Ottenheijm CA, Shen S, van der Pijl RJ, van der Velden J, Paulus WJ, Eringa EC. Waddingham MT, et al. Among authors: da silva goncalves bos d. Physiol Rep. 2023 Nov;11(22):e15788. doi: 10.14814/phy2.15788. Physiol Rep. 2023. PMID: 37985159 Free PMC article. Clinical Trial.
Increased MAO-A Activity Promotes Progression of Pulmonary Arterial Hypertension.
Sun XQ, Peters EL, Schalij I, Axelsen JB, Andersen S, Kurakula K, Gomez-Puerto MC, Szulcek R, Pan X, da Silva Goncalves Bos D, Schiepers REJ, Andersen A, Goumans MJ, Vonk Noordegraaf A, van der Laarse WJ, de Man FS, Bogaard HJ. Sun XQ, et al. Among authors: da silva goncalves bos d. Am J Respir Cell Mol Biol. 2021 Mar;64(3):331-343. doi: 10.1165/rcmb.2020-0105OC. Am J Respir Cell Mol Biol. 2021. PMID: 33264068
α7 Nicotinic acetylcholine receptor mediates right ventricular fibrosis and diastolic dysfunction in pulmonary hypertension.
Vang A, da Silva Gonçalves Bos D, Fernandez-Nicolas A, Zhang P, Morrison AR, Mancini TJ, Clements RT, Polina I, Cypress MW, Jhun BS, Hawrot E, Mende U, O-Uchi J, Choudhary G. Vang A, et al. Among authors: da silva goncalves bos d. JCI Insight. 2021 Jun 22;6(12):e142945. doi: 10.1172/jci.insight.142945. JCI Insight. 2021. PMID: 33974567 Free PMC article.
Nintedanib improves cardiac fibrosis but leaves pulmonary vascular remodelling unaltered in experimental pulmonary hypertension.
Rol N, de Raaf MA, Sun XQ, Kuiper VP, da Silva Gonçalves Bos D, Happé C, Kurakula K, Dickhoff C, Thuillet R, Tu L, Guignabert C, Schalij I, Lodder K, Pan X, Herrmann FE, van Nieuw Amerongen GP, Koolwijk P, Vonk-Noordegraaf A, de Man FS, Wollin L, Goumans MJ, Szulcek R, Bogaard HJ. Rol N, et al. Among authors: da silva goncalves bos d. Cardiovasc Res. 2019 Feb 1;115(2):432-439. doi: 10.1093/cvr/cvy186. Cardiovasc Res. 2019. PMID: 30032282
Prevention of progression of pulmonary hypertension by the Nur77 agonist 6-mercaptopurine: role of BMP signalling.
Kurakula K, Sun XQ, Happé C, da Silva Goncalves Bos D, Szulcek R, Schalij I, Wiesmeijer KC, Lodder K, Tu L, Guignabert C, de Vries CJM, de Man FS, Vonk Noordegraaf A, Ten Dijke P, Goumans MJ, Bogaard HJ. Kurakula K, et al. Among authors: da silva goncalves bos d. Eur Respir J. 2019 Sep 29;54(3):1802400. doi: 10.1183/13993003.02400-2018. Print 2019 Sep. Eur Respir J. 2019. PMID: 31273046 Free article.
Renal Denervation Reduces Pulmonary Vascular Remodeling and Right Ventricular Diastolic Stiffness in Experimental Pulmonary Hypertension.
da Silva Gonçalves Bos D, Happé C, Schalij I, Pijacka W, Paton JFR, Guignabert C, Tu L, Thuillet R, Bogaard HJ, van Rossum AC, Vonk-Noordegraaf A, de Man FS, Handoko ML. da Silva Gonçalves Bos D, et al. JACC Basic Transl Sci. 2017 Feb 1;2(1):22-35. doi: 10.1016/j.jacbts.2016.09.007. eCollection 2017 Feb. JACC Basic Transl Sci. 2017. PMID: 29034356 Free PMC article.
Contribution of Impaired Parasympathetic Activity to Right Ventricular Dysfunction and Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension.
da Silva Gonçalves Bós D, Van Der Bruggen CEE, Kurakula K, Sun XQ, Casali KR, Casali AG, Rol N, Szulcek R, Dos Remedios C, Guignabert C, Tu L, Dorfmüller P, Humbert M, Wijnker PJM, Kuster DWD, van der Velden J, Goumans MJ, Bogaard HJ, Vonk-Noordegraaf A, de Man FS, Handoko ML. da Silva Gonçalves Bós D, et al. Circulation. 2018 Feb 27;137(9):910-924. doi: 10.1161/CIRCULATIONAHA.117.027451. Epub 2017 Nov 22. Circulation. 2018. PMID: 29167228
Right Ventricular Myocardial Stiffness in Experimental Pulmonary Arterial Hypertension: Relative Contribution of Fibrosis and Myofibril Stiffness.
Rain S, Andersen S, Najafi A, Gammelgaard Schultz J, da Silva Gonçalves Bós D, Handoko ML, Bogaard HJ, Vonk-Noordegraaf A, Andersen A, van der Velden J, Ottenheijm CA, de Man FS. Rain S, et al. Among authors: da silva goncalves bos d. Circ Heart Fail. 2016 Jul;9(7):e002636. doi: 10.1161/CIRCHEARTFAILURE.115.002636. Circ Heart Fail. 2016. PMID: 27370069 Free PMC article.