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Asthmatic farm children show increased CD3+CD8low T-cells compared to non-asthmatic farm children.
Twardziok M, Schröder PC, Krusche J, Casaca VI, Illi S, Böck A, Loss GJ, Kabesch M, Toncheva AA, Roduit C, Depner M, Genuneit J, Renz H, Roponen M, Weber J, Braun-Fahrländer C, Riedler J, Lauener R, Vuitton DA, Dalphin JC, Pekkanen J, von Mutius E, Schaub B; PASTURE Study Group:; Hyvärinen A, Karvonen AM, Kirjavainen PV, Remes S, Kaulek V, Dalphin ML, Ege M, Pfefferle PI, Doekes G. Twardziok M, et al. Among authors: schroder pc. Clin Immunol. 2017 Oct;183:285-292. doi: 10.1016/j.clim.2017.09.009. Epub 2017 Sep 13. Clin Immunol. 2017. PMID: 28917722 No abstract available.
Circulating Dendritic Cells, Farm Exposure and Asthma at Early Age.
Kääriö H, Nieminen JK, Karvonen AM, Huttunen K, Schröder PC, Vaarala O, von Mutius E, Pfefferle PI, Schaub B, Pekkanen J, Hirvonen MR, Roponen M. Kääriö H, et al. Among authors: schroder pc. Scand J Immunol. 2016 Jan;83(1):18-25. doi: 10.1111/sji.12389. Scand J Immunol. 2016. PMID: 26368653 Free article.
TNF-α-induced protein 3 is a key player in childhood asthma development and environment-mediated protection.
Krusche J, Twardziok M, Rehbach K, Böck A, Tsang MS, Schröder PC, Kumbrink J, Kirchner T, Xing Y, Riedler J, Dalphin JC, Pekkanen J, Lauener R, Roponen M, Li J, Wong CK, Wong GWK, Schaub B; PASTURE study group. Krusche J, et al. Among authors: schroder pc. J Allergy Clin Immunol. 2019 Dec;144(6):1684-1696.e12. doi: 10.1016/j.jaci.2019.07.029. Epub 2019 Aug 2. J Allergy Clin Immunol. 2019. PMID: 31381928 Clinical Trial.
A switch in regulatory T cells through farm exposure during immune maturation in childhood.
Schröder PC, Illi S, Casaca VI, Lluis A, Böck A, Roduit C, Depner M, Frei R, Genuneit J, Pfefferle PI, Roponen M, Weber J, Braun-Fahrländer C, Riedler J, Dalphin JC, Pekkanen J, Lauener R, von Mutius E, Schaub B; PASTURE study group. Schröder PC, et al. Allergy. 2017 Apr;72(4):604-615. doi: 10.1111/all.13069. Epub 2016 Nov 17. Allergy. 2017. PMID: 27732759
IL-33 polymorphisms are associated with increased risk of hay fever and reduced regulatory T cells in a birth cohort.
Schröder PC, Casaca VI, Illi S, Schieck M, Michel S, Böck A, Roduit C, Frei R, Lluis A, Genuneit J, Pfefferle P, Roponen M, Weber J, Braun-Fahrländer C, Riedler J, Lauener R, Vuitton DA, Dalphin JC, Pekkanen J, von Mutius E, Kabesch M, Schaub B; PASTURE Study group. Schröder PC, et al. Pediatr Allergy Immunol. 2016 Nov;27(7):687-695. doi: 10.1111/pai.12597. Epub 2016 Jul 12. Pediatr Allergy Immunol. 2016. PMID: 27171815