Abstract
Sixteen autologous stem cell transplant recipients received three vaccinations with conjugated haemophilus influenzae type b vaccine. Quantitative and qualitative aspects of the antibody response were studied. The vaccination schedule resulted in high antibody response rates and functional maturation of antibodies, as measured by antibody avidity and phagocytosis-inducing capacity.
Publication types
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Comparative Study
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Letter
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Antibodies, Bacterial / biosynthesis*
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Antibodies, Bacterial / blood
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Bacterial Capsules
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Haemophilus Infections / blood
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Haemophilus Infections / immunology
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Haemophilus Infections / prevention & control
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Haemophilus Vaccines / administration & dosage
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Haemophilus Vaccines / immunology*
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Haemophilus Vaccines / therapeutic use*
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Haemophilus influenzae type b / immunology
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Haemophilus influenzae type b / metabolism*
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Humans
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Polysaccharides, Bacterial / administration & dosage
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Polysaccharides, Bacterial / immunology*
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Polysaccharides, Bacterial / therapeutic use*
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Stem Cell Transplantation / adverse effects
Substances
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Antibodies, Bacterial
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Haemophilus Vaccines
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Haemophilus influenzae type b polysaccharide vaccine
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Polysaccharides, Bacterial