Pettipher R[au] - Search Results

Year	Number of Results
1990	1
1992	1
2002	1
2005	5
2006	3
2007	4
2008	2
2009	3
2010	1
2011	3
2012	7
2013	2
2014	2
2015	1
2024	0

1

Antagonists of the prostaglandin D2 receptor CRTH2.

Pettipher R, Hansel TT. Pettipher R, et al. Drug News Perspect. 2008 Jul-Aug;21(6):317-22. doi: 10.1358/dnp.2008.21.6.1246831. Drug News Perspect. 2008. PMID: 18836589 Free article. Review.

2

The roles of the prostaglandin D(2) receptors DP(1) and CRTH2 in promoting allergic responses.

Pettipher R. Pettipher R. Br J Pharmacol. 2008 Mar;153 Suppl 1(Suppl 1):S191-9. doi: 10.1038/sj.bjp.0707488. Epub 2007 Oct 29. Br J Pharmacol. 2008. PMID: 17965752 Free PMC article. Review.

3

Antagonism of the prostaglandin D2 receptors DP1 and CRTH2 as an approach to treat allergic diseases.

Pettipher R, Hansel TT, Armer R. Pettipher R, et al. Nat Rev Drug Discov. 2007 Apr;6(4):313-25. doi: 10.1038/nrd2266. Nat Rev Drug Discov. 2007. PMID: 17396136 Review.

4

Update on the development of antagonists of chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2). From lead optimization to clinical proof-of-concept in asthma and allergic rhinitis.

Pettipher R, Whittaker M. Pettipher R, et al. J Med Chem. 2012 Apr 12;55(7):2915-31. doi: 10.1021/jm2013997. Epub 2012 Feb 13. J Med Chem. 2012. PMID: 22224640 Review. No abstract available.

5

Identification of G-protein-coupled receptors involved in inflammatory disease by genetic association studies.

Pettipher R, Mangion J, Hunter MG, Mackay I. Pettipher R, et al. Curr Opin Pharmacol. 2005 Aug;5(4):412-7. doi: 10.1016/j.coph.2005.03.005. Curr Opin Pharmacol. 2005. PMID: 15955737 Review.

6

Inhibition of the asthmatic allergen challenge response by the CRTH2 antagonist OC000459.

Singh D, Cadden P, Hunter M, Pearce Collins L, Perkins M, Pettipher R, Townsend E, Vinall S, O'Connor B. Singh D, et al. Among authors: pettipher r. Eur Respir J. 2013 Jan;41(1):46-52. doi: 10.1183/09031936.00092111. Epub 2012 Apr 10. Eur Respir J. 2013. PMID: 22496329 Free article. Clinical Trial.

7

The application of genetics to the discovery of better medicines.

Pettipher R, Cardon LR. Pettipher R, et al. Pharmacogenomics. 2002 Mar;3(2):257-63. doi: 10.1517/14622416.3.2.257. Pharmacogenomics. 2002. PMID: 11972446 Review.

8

Heightened response of eosinophilic asthmatic patients to the CRTH2 antagonist OC000459.

Pettipher R, Hunter MG, Perkins CM, Collins LP, Lewis T, Baillet M, Steiner J, Bell J, Payton MA. Pettipher R, et al. Allergy. 2014 Sep;69(9):1223-32. doi: 10.1111/all.12451. Epub 2014 Jul 14. Allergy. 2014. PMID: 24866478 Clinical Trial.

9

Anti-eosinophil activity and clinical efficacy of the CRTH2 antagonist OC000459 in eosinophilic esophagitis.

Straumann A, Hoesli S, Bussmann Ch, Stuck M, Perkins M, Collins LP, Payton M, Pettipher R, Hunter M, Steiner J, Simon HU. Straumann A, et al. Among authors: pettipher r. Allergy. 2013 Mar;68(3):375-85. doi: 10.1111/all.12096. Epub 2013 Feb 5. Allergy. 2013. PMID: 23379537 Clinical Trial.

10

Indole-3-acetic acid antagonists of the prostaglandin D2 receptor CRTH2.

Armer RE, Ashton MR, Boyd EA, Brennan CJ, Brookfield FA, Gazi L, Gyles SL, Hay PA, Hunter MG, Middlemiss D, Whittaker M, Xue L, Pettipher R. Armer RE, et al. Among authors: pettipher r. J Med Chem. 2005 Oct 6;48(20):6174-7. doi: 10.1021/jm050519b. J Med Chem. 2005. PMID: 16190744

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