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2002 1
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Page 1
Inhibitors of cathepsin C (dipeptidyl peptidase I).
Laine DI, Busch-Petersen J. Laine DI, et al. Expert Opin Ther Pat. 2010 Apr;20(4):497-506. doi: 10.1517/13543771003657172. Expert Opin Ther Pat. 2010. PMID: 20205619 Review.
An asymmetric phase-transfer dihydroxylation reaction.
Bhunnoo RA, Hu Y, Lainé DI, Brown RC. Bhunnoo RA, et al. Among authors: laine di. Angew Chem Int Ed Engl. 2002 Sep 16;41(18):3479-80. doi: 10.1002/1521-3773(20020916)41:18<3479::AID-ANIE3479>3.0.CO;2-O. Angew Chem Int Ed Engl. 2002. PMID: 12298071 No abstract available.
Biphenyl amide p38 kinase inhibitors 3: Improvement of cellular and in vivo activity.
Angell R, Aston NM, Bamborough P, Buckton JB, Cockerill S, deBoeck SJ, Edwards CD, Holmes DS, Jones KL, Laine DI, Patel S, Smee PA, Smith KJ, Somers DO, Walker AL. Angell R, et al. Among authors: laine di. Bioorg Med Chem Lett. 2008 Aug 1;18(15):4428-32. doi: 10.1016/j.bmcl.2008.06.048. Epub 2008 Jun 18. Bioorg Med Chem Lett. 2008. PMID: 18614366
Design, synthesis and structure-activity relationship of N-substituted tropane muscarinic acetylcholine receptor antagonists.
Lainé DI, Yan H, Xie H, Davis RS, Dufour J, Widdowson KL, Palovich MR, Wan Z, Foley JJ, Schmidt DB, Hunsberger GE, Burman M, Bacon AM, Webb EF, Luttmann MA, Salmon M, Sarau HM, Umbrecht ST, Landis PS, Peck BJ, Busch-Petersen J. Lainé DI, et al. Bioorg Med Chem Lett. 2012 May 1;22(9):3366-9. doi: 10.1016/j.bmcl.2012.02.015. Epub 2012 Feb 15. Bioorg Med Chem Lett. 2012. PMID: 22460029
Pharmacological characterization of GSK573719 (umeclidinium): a novel, long-acting, inhaled antagonist of the muscarinic cholinergic receptors for treatment of pulmonary diseases.
Salmon M, Luttmann MA, Foley JJ, Buckley PT, Schmidt DB, Burman M, Webb EF, DeHaas CJ, Kotzer CJ, Barrett VJ, Slack RJ, Sarau HM, Palovich MR, Lainé DI, Hay DW, Rumsey WL. Salmon M, et al. Among authors: laine di. J Pharmacol Exp Ther. 2013 May;345(2):260-70. doi: 10.1124/jpet.112.202051. Epub 2013 Feb 22. J Pharmacol Exp Ther. 2013. PMID: 23435542
M3 muscarinic acetylcholine receptor antagonists: SAR and optimization of bi-aryl amines.
Budzik B, Wang Y, Shi D, Wang F, Xie H, Wan Z, Zhu C, Foley JJ, Nuthulaganti P, Kallal LA, Sarau HM, Morrow DM, Moore ML, Rivero RA, Palovich M, Salmon M, Belmonte KE, Laine DI, Jin J. Budzik B, et al. Among authors: laine di. Bioorg Med Chem Lett. 2009 Mar 15;19(6):1686-90. doi: 10.1016/j.bmcl.2009.01.098. Epub 2009 Feb 4. Bioorg Med Chem Lett. 2009. PMID: 19243945
16 results