Abstract
We describe the case of a 12-year-old girl who developed lymphocytic interstitial pneumonitis at 2 years of age which preceded polyarticular rheumatoid factor (RF) positive juvenile arthritis. Her disease had a chronic active course, but showed a good response to combination therapy. The pathogenesis of these two immune processes and of the lung involvement in juvenile arthritis is discussed.
MeSH terms
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Anti-Inflammatory Agents
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Antirheumatic Agents / therapeutic use
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Arthritis, Juvenile / diagnosis
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Arthritis, Juvenile / drug therapy
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Arthritis, Juvenile / etiology*
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Biopsy
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Child
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Drug Therapy, Combination
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Female
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Humans
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Hydroxychloroquine / therapeutic use
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Lung / diagnostic imaging
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Lung / pathology
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Lung Diseases, Interstitial / complications*
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Lung Diseases, Interstitial / diagnosis
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Lung Diseases, Interstitial / drug therapy
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Lymphocytosis / complications*
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Lymphocytosis / diagnosis
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Lymphocytosis / drug therapy
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Methotrexate / therapeutic use
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Prednisone / therapeutic use
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Tomography, X-Ray Computed
Substances
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Anti-Inflammatory Agents
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Antirheumatic Agents
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Hydroxychloroquine
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Prednisone
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Methotrexate