No relation between apolipoprotein E alleles and obstructive sleep apnea

S Saarelainen; T Lehtimäki; E Kallonen; K Laasonen; T Poussa; M M Nieminen

doi:10.1111/j.1399-0004.1998.tb02663.x

No relation between apolipoprotein E alleles and obstructive sleep apnea

Clin Genet. 1998 Feb;53(2):147-8. doi: 10.1111/j.1399-0004.1998.tb02663.x.

Authors

S Saarelainen¹, T Lehtimäki, E Kallonen, K Laasonen, T Poussa, M M Nieminen

Affiliation

¹ Department of Pulmonary Diseases, Tampere University Hospital and Medical School, University of Tampere, Finland.

PMID: 9611077
DOI: 10.1111/j.1399-0004.1998.tb02663.x

Abstract

Apolipoprotein E (ApoE) is a genetic risk factor influencing the development of cardiovascular diseases and Alzheimer's disease. Patients with obstructive sleep apnea (OSA) suffer an excess mortality and morbidity from cardiovascular diseases. The frequencies of ApoE alleles were determined in 291 patients with OSA and 728 controls. The distribution of ApoE alleles and genotypes showed no difference between OSA and controls.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Aged
Alleles*
Apolipoproteins E / genetics*
Female
Humans
Male
Middle Aged
Sleep Apnea Syndromes / genetics*
Sleep Apnea Syndromes / metabolism

Substances

Apolipoproteins E