Abstract
Sleep apnea is associated with abnormalities in metabolic function. First, there is a strong epidemiological link between central obesity and sleep apnea. Some evidence suggests that sleep apnea may promote weight gain or prevent weight loss by several mechanisms: reduction in anabolic (growth hormone and testosterone) hormone secretion, influences on energy balance and insulin sensitivity, and altered central serotonergic tone.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Energy Metabolism
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Female
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Growth Hormone / deficiency
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Growth Hormone-Releasing Hormone / metabolism
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Humans
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Insulin-Like Growth Factor I / metabolism
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Male
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Obesity / complications
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Positive-Pressure Respiration
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Sex Factors
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Sleep Apnea Syndromes / etiology
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Sleep Apnea Syndromes / metabolism*
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Sleep Apnea Syndromes / therapy
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Testosterone / metabolism
Substances
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Testosterone
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Insulin-Like Growth Factor I
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Growth Hormone
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Growth Hormone-Releasing Hormone