Abstract
Aerosolized tobramycin is well tolerated in children and adults with cystic fibrosis (CF). It represents a potential alternative to intravenous administration of antibiotics to control respiratory infection with Pseudomonas aeruginosa. Although its exact role in acute therapy for a CF exacerbation is not known, it has been shown to improve lung function and reduce the frequency of exacerbations in the chronic stable outpatient.
MeSH terms
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Administration, Inhalation
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Aerosols
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Bronchial Diseases / drug therapy*
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Bronchial Diseases / microbiology
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Bronchial Diseases / physiopathology
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Cystic Fibrosis / complications
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Cystic Fibrosis / drug therapy*
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Cystic Fibrosis / physiopathology
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Female
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Humans
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Male
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Pseudomonas Infections / drug therapy*
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Pseudomonas Infections / etiology
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Pseudomonas Infections / physiopathology
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Randomized Controlled Trials as Topic
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Tobramycin / administration & dosage*
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Tobramycin / therapeutic use*