Reversible interstitial pneumonitis associated with low dose bleomycin

Chest. 1975 Aug;68(2):265-7. doi: 10.1378/chest.68.2.265.

Abstract

A patient with nodular histiocytic lymphoma was treated with bleomycin; she later developed interstitial pneumonitis documented by lung biopsy. The dose of bleomycin producing this complication was lower than previously reported, and the pulmonary toxicity was apparently completely reversible.

MeSH terms

  • Abdominal Neoplasms / drug therapy
  • Bleomycin / adverse effects*
  • Bleomycin / therapeutic use
  • Doxorubicin / therapeutic use
  • Female
  • Humans
  • Lymphatic Metastasis
  • Lymphoma, Large B-Cell, Diffuse / drug therapy
  • Middle Aged
  • Prednisone / therapeutic use
  • Pulmonary Fibrosis / chemically induced*
  • Pulmonary Fibrosis / diagnostic imaging
  • Pulmonary Fibrosis / drug therapy
  • Radiography
  • Remission, Spontaneous

Substances

  • Bleomycin
  • Doxorubicin
  • Prednisone