The diversity of asthma phenotypes increases its complexity. Animal models represent a useful tool to elucidate the pathophysiological mechanisms involved in both allergic and nonallergic asthma, as well as to identify potential targets for the development of new treatments. Among all available animal models, mice offer significant advantages for the study of asthma. In this chapter, the applications of mouse models to the study of asthma will be reviewed.
Keywords: Animal models; Asthma; Challenge; Mouse; Sensitization.