Family history of immigration from a tuberculosis endemic country and low family income are associated with a higher BCG vaccination coverage in Ile-de-France region, France

Vaccine. 2013 Nov 19;31(48):5666-71. doi: 10.1016/j.vaccine.2013.09.059. Epub 2013 Oct 10.

Abstract

After withdrawal of multipuncture BCG device from the French market in January 2006, vaccination coverage (VC) with the intradermal device has dropped and since remained sub-optimal in Ile-de-France, the only region of mainland France where BCG is recommended to all children. We conducted a cross-sectional study to identify socio-economic factors associated with BCG VC in children of Paris metropolitan area born after January 2006. Two-stage random sampling was used to include 425 children up to 5 years old from Paris and its suburbs. Information was collected through face-to-face interviews and vaccination status confirmed by a vaccination document. Poisson regression analyzed the association between VC and potential determinants. VC of children from families with the lowest incomes (first quartile of family income/consumption unit (CU) (<883 €) was close to 100% regardless of family origin. In families with higher incomes (≥ 883 €/CU), VC was significantly higher among children born to families from a tuberculosis highly endemic country (98.2%) compared with other children (76.2%) (p=0.004). Children of low socio-economic background as well as those with a family history of immigration, regardless of family income, are correctly identified as being at high risk of tuberculosis and properly vaccinated with BCG in this area.

Keywords: BCG; France; Immunization coverage; Socioeconomic determinants.

MeSH terms

  • Adult
  • BCG Vaccine / administration & dosage*
  • BCG Vaccine / immunology*
  • Child, Preschool
  • Cohort Studies
  • Emigrants and Immigrants*
  • Emigration and Immigration
  • Female
  • Humans
  • Income
  • Infant
  • Infant, Newborn
  • Male
  • Paris
  • Socioeconomic Factors
  • Tuberculosis / prevention & control*
  • Vaccination / statistics & numerical data*

Substances

  • BCG Vaccine