Fatal outcome of a disseminated dual infection with drug-resistant Mycoplasma hominis and Ureaplasma parvum originating from a septic arthritis in an immunocompromised patient

Colin R MacKenzie; Nicole Nischik; Rainer Kram; Rüdiger Krauspe; Marcus Jäger; Birgit Henrich

doi:10.1016/j.ijid.2010.02.2253

Fatal outcome of a disseminated dual infection with drug-resistant Mycoplasma hominis and Ureaplasma parvum originating from a septic arthritis in an immunocompromised patient

Int J Infect Dis. 2010 Sep:14 Suppl 3:e307-9. doi: 10.1016/j.ijid.2010.02.2253. Epub 2010 Jun 15.

Authors

Colin R MacKenzie¹, Nicole Nischik, Rainer Kram, Rüdiger Krauspe, Marcus Jäger, Birgit Henrich

Affiliation

¹ Institute of Medical Microbiology and Hospital Hygiene, University Hospital, Heinrich-Heine-University, Universitätsstraße 1, Düsseldorf, Germany. colin.mackenzie@uni-duesseldorf.de

PMID: 20554466
DOI: 10.1016/j.ijid.2010.02.2253

Abstract

Mycoplasma hominis and Ureaplasma parvum are rare causes of severe and fatal infections. The diagnosis of infection with mycoplasma is dependent on clinical suspicion and microbiological diagnosis, and often relies on molecular methods that do not readily detect antibiotic resistance. This may be of increasing importance as illustrated in the case below.

Publication types

Case Reports

MeSH terms

Arthritis, Infectious / diagnosis
Arthritis, Infectious / drug therapy
Arthritis, Infectious / microbiology*
Arthroplasty, Replacement, Hip / adverse effects
Cross Infection / diagnosis
Cross Infection / microbiology
Fatal Outcome
Humans
Immunocompromised Host
Male
Microbial Sensitivity Tests
Middle Aged
Mycoplasma Infections / diagnosis
Mycoplasma Infections / drug therapy
Mycoplasma Infections / microbiology*
Mycoplasma hominis* / drug effects
Mycoplasma hominis* / genetics
Mycoplasma hominis* / isolation & purification
Ureaplasma Infections / diagnosis
Ureaplasma Infections / drug therapy
Ureaplasma Infections / microbiology*