The transcriptome of human monocyte subsets begins to emerge

J Biol. 2009;8(11):99. doi: 10.1186/jbiol206. Epub 2009 Dec 23.

Abstract

Human monocytes can be divided into subsets according to their expression or lack of the cell-surface antigen CD16. In papers published recently in the Journal of Proteome Research and in BMC Genomics, two groups publish independent transcriptome analyses of CD16(+) and CD16(-) monocytes, with revealing results.

Publication types

  • Review

MeSH terms

  • GPI-Linked Proteins / genetics
  • GPI-Linked Proteins / metabolism
  • Gene Expression Regulation / physiology*
  • Humans
  • Monocytes / classification*
  • Monocytes / metabolism*
  • Receptors, IgG / genetics
  • Receptors, IgG / metabolism
  • Transcriptome*

Substances

  • FCGR3B protein, human
  • GPI-Linked Proteins
  • Receptors, IgG