Abstract
14 patients, aged 2-28 years, with neuromuscular disorders and symptomatic sleep hypoventilation received night-time intermittent positive-pressure ventilation with a nasal mask. 9 were treated de novo and 5 had previously been maintained on a cuirass or iron lung. Nasal ventilation was very effective in 10 patients but was not tolerated in 4 of the 5 youngest patients. Nasal ventilation was preferable to other methods of ventilation because the system was non-invasive, quiet, portable, and easy to use and because it allowed considerable independence.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acute Disease
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Adolescent
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Adult
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Blood Gas Analysis
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Child
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Child, Preschool
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Circadian Rhythm
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Evaluation Studies as Topic
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Female
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Follow-Up Studies
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Humans
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Hypoventilation / etiology
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Hypoventilation / physiopathology
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Hypoventilation / therapy*
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Intermittent Positive-Pressure Breathing / methods*
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Male
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Muscular Dystrophies / blood
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Muscular Dystrophies / complications
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Muscular Dystrophies / physiopathology
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Neuromuscular Diseases / blood
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Neuromuscular Diseases / complications*
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Neuromuscular Diseases / physiopathology
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Positive-Pressure Respiration / methods*
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Retrospective Studies
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Sleep Apnea Syndromes / etiology
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Sleep Apnea Syndromes / physiopathology
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Sleep Apnea Syndromes / therapy*
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Vital Capacity