Objective: To describe a case of intracytoplasmic sperm injection (ICSI) with testicular sperm in men with immotile cilia syndrome and to discuss the role of micromanipulation in the treatment of these patients.
Design: Case report.
Setting: Private infertility clinic and assisted reproduction unit.
Patient(s): Couple with male factor infertility due to Kartagener's/immotile cilia syndrome.
Intervention(s): The patient's partner underwent ICSI with testicular sperm.
Main outcome measure(s): Semen characteristics, sperm viability, fertilization and cleavage rate, pregnancy, and birth after ICSI.
Result(s): With testicular sperm, the two pronuclear fertilization rates were 53%. ICSI was successful in the first cycle. The uncomplicated pregnancy resulted in the birth of two healthy children, male/female twins.
Conclusion(s): With testicular sperm, successful oocyte fertilization after ICSI in couples with male Kartagener or immotile cilia syndrome is possible with nonprogressive motile sperm resulting in clinically healthy offsprings.