The development of the ultrathin bronchoscope has provided a means of providing flexible endoscopic intubation for the neonate and small infant. We report our experience of 26 such endoscopic intubations in 23 neonates with birth weights from 1,200 to 4,600 g and post-conceptional ages varying from 31.5 to 60 weeks. The most common indications for the procedure were dysmorphic airways with variable degrees of micrognathia, acquired airway lesions, and severe degrees of hydrocephalus. With the use of the current 2.2 mm and 2.7 mm diameter instruments, it is now possible to utilize this technique with 2.5 mm endotracheal tubes. There were no failed procedures and no evidence of laryngospasm, the most frequent adverse effect being a transient fall in oxygen saturation. The procedure as practiced by experienced individuals is well tolerated and is an important adjunct for intubation of neonates with dysmorphic upper airways or other disorders that prevent adequate visualization of the larynx.