[A case of endobronchial mucormycosis with peculiar bronchoscopic findings]

Nihon Kokyuki Gakkai Zasshi. 2004 Feb;42(2):181-4.
[Article in Japanese]

Abstract

Small cell lung cancer was diagnosed in a 54-year-old man in 1997. He had received 5 cycles of systemic chemotherapy and thoracic irradiation since 1997, and a favorable response had been achieved. In August 2001, pro-GRP was again elevated, and he was readmitted. Bronchoscopic findings revealed a white dendritic endobronchial mass on a cheese-like plug obstructing the left upper bronchus division. Numerous mucor hyphe and cancer cells were detected by transbronchial biopsy, and a fungal culture disclosed mucor. Although no antifungal drug was administered, the bronchial lesion disappeared after removal with biopsy forceps and 2 cycles of systemic anticancer chemotherapy. Endobronchial involvement of mucormycosis is rare and this case is unique because of the peculiar bronchoscopic finding with the endobronchial lesion.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Biopsy / methods
  • Bronchial Diseases / etiology*
  • Bronchial Diseases / pathology*
  • Bronchial Diseases / therapy
  • Bronchoscopy*
  • Carcinoma, Small Cell / complications*
  • Carcinoma, Small Cell / therapy
  • Cisplatin / administration & dosage
  • Humans
  • Immunocompromised Host
  • Lung Neoplasms / complications*
  • Lung Neoplasms / therapy
  • Male
  • Middle Aged
  • Mucormycosis / etiology*
  • Mucormycosis / pathology*
  • Mucormycosis / therapy
  • Paclitaxel / administration & dosage
  • Rhizomucor
  • Surgical Instruments
  • Treatment Outcome

Substances

  • Paclitaxel
  • Cisplatin