Could isoenzyme-selective phosphodiesterase inhibitors render bronchodilator therapy redundant in the treatment of bronchial asthma?

Biochem Pharmacol. 1992 May 28;43(10):2041-51. doi: 10.1016/0006-2952(92)90160-k.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • 3',5'-Cyclic-AMP Phosphodiesterases / antagonists & inhibitors*
  • Animals
  • Asthma / drug therapy*
  • Asthma / prevention & control
  • Bronchodilator Agents / therapeutic use*
  • Eosinophils / drug effects
  • Humans
  • Inflammation / prevention & control
  • Isoenzymes / antagonists & inhibitors
  • Macrophages / drug effects
  • Mast Cells / drug effects
  • Neutrophils / drug effects
  • Phosphodiesterase Inhibitors / pharmacology*
  • T-Lymphocytes / drug effects

Substances

  • Bronchodilator Agents
  • Isoenzymes
  • Phosphodiesterase Inhibitors
  • 3',5'-Cyclic-AMP Phosphodiesterases