Fibrosing mediastinitis secondary to zygomycosis in a twenty-two-month-old child

Pediatr Infect Dis J. 2002 May;21(5):441-2. doi: 10.1097/00006454-200205000-00023.

Abstract

We report the case of a 22-month-old immunocompetent male child with fibrosing mediastinitis secondary to zygomycosis, an unusual presentation of a rare fungal infection. This patient was successfully treated with amphotericin B and itraconazole for 20 weeks. Stenting of the superior vena cava was helpful in relieving the patient's superior vena cava syndrome.

Publication types

  • Case Reports

MeSH terms

  • Amphotericin B / therapeutic use*
  • Antifungal Agents / therapeutic use*
  • Fibrosis
  • Humans
  • Infant
  • Itraconazole / therapeutic use*
  • Male
  • Mediastinitis / drug therapy
  • Mediastinitis / etiology*
  • Mediastinitis / microbiology
  • Stents
  • Superior Vena Cava Syndrome / drug therapy
  • Superior Vena Cava Syndrome / surgery
  • Treatment Outcome
  • Zygomycosis / complications*
  • Zygomycosis / drug therapy

Substances

  • Antifungal Agents
  • Itraconazole
  • Amphotericin B