Abstract
Recent work implicates Toll-like receptor (TLR) proteins as regulators of innate immune cell activation induced by Mycobacterium tuberculosis, which continues to ravage nearly one-third of the world's population. Novel insights into how TLR proteins may dictate the nature and extent of cellular immune responses against this pathogen will be discussed.
MeSH terms
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Animals
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Antigen Presentation
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Antigen-Presenting Cells / immunology
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Apoptosis
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Drosophila Proteins*
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Humans
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Immunity, Innate*
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Membrane Glycoproteins / agonists
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Membrane Glycoproteins / metabolism*
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Mycobacterium tuberculosis / immunology*
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Mycobacterium tuberculosis / pathogenicity
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Receptors, Cell Surface / agonists
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Receptors, Cell Surface / metabolism*
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Signal Transduction
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Toll-Like Receptors
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Tuberculosis / immunology*
Substances
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Drosophila Proteins
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Membrane Glycoproteins
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Receptors, Cell Surface
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Toll-Like Receptors