The acquisition techniques, including some important dosimetric considerations, and the reconstruction methods reviewing the tomographic, bronchographic and endoscopic rendering techniques are first taken into consideration. They are applied to the most usual problems and diseases encountered in the daily activityThe main purpose of this review, which merges the modern technology of spiral (helical) CT with the multislice acquisition in the very near future, consists in delivering, whenever possible, an integrated diagnostic and therapeutic approach of imaging, endoscopy and surgery.