Diagnosis of left-ventricular dysfunction from induced sputum examination

Lancet. 1999 Sep 4;354(9181):833-4. doi: 10.1016/S0140-6736(99)80018-X.

Abstract

We have shown that the examination of induced sputum for haemosiderin-laden macrophages is sensitive and specific for detecting raised left-sided filling pressures associated with left-ventricular dysfunction.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Cross-Sectional Studies
  • Echocardiography
  • Female
  • Hemosiderin / metabolism
  • Humans
  • Macrophages / metabolism
  • Male
  • Middle Aged
  • Pilot Projects
  • Prospective Studies
  • Sensitivity and Specificity
  • Sputum / cytology*
  • Ventricular Dysfunction, Left / diagnosis*

Substances

  • Hemosiderin