Fat Embolism Syndrome Caused by Vegetable Oil Injection

Hiroshi KIYOKAWA; Kenta UTSUMI; Kazushige MINEMURA; Ikuma KASUGA; Yasushi TORII; Makoto YONEMARU; Yuichi ICHINOSE; Keisuke TOYAMA

doi:10.2169/internalmedicine.34.380

Hiroshi KIYOKAWA, Kenta UTSUMI, Kazushige MINEMURA, Ikuma KASUGA, Yasushi TORII, Makoto YONEMARU, Yuichi ICHINOSE, Keisuke TOYAMA

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Keywords: augmentation mammaplasty, oleic acid, acute respiratory distress, bronchoalveolar lavage, transbronchial lung biopsy, Nile blue stain

JOURNAL FREE ACCESS

1995 Volume 34 Issue 5 Pages 380-383

DOI https://doi.org/10.2169/internalmedicine.34.380

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Abstract

We present a case of fat embolism syndrome following vegetable oil injection for augmentation mammaplasty. Although vegetable oil is a stable neutral fat under usual storage conditions, it caused fat embolism and pulmonary injury in this patient. We investigated this mechanism by compound analysis of the injected oil, transbronchial lung biopsy and special staining of alveolar macrophages. This is the first description of the human response to vegetable oil injection. These data should aid in the investigation of the side effects of many types of lipids which may be applied to humans for various purposes in the future.
(Internal Medicine 34: 380-383, 1995)

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