Chest
Clinical InvestigationsA Comparison of Gender Differences in Health-Related Quality of Life in Acute and Chronic Coughers
Section snippets
Materials and Methods
To compare the HRQOL of women with AC to that of men with AC, pooled data, which were prospectively collected from 62 subjects who presented to primary care physicians complaining of AC, were analyzed from two time periods. AC was defined as a cough < 3 weeks in duration. Data from the first 30 subjects had been collected consecutively and prospectively during psychometric testing of the CQLQ.5 These data have not previously been reported. Data from the remaining 32 subjects were consecutively
Characteristics of Acute Coughers
This cohort was composed of 62 subjects. Of the 62 subjects, 32 (51.6%) were women with a mean (± SD) age of 42.2 ± 14.3 years, and 30 (48.4%) were men with a mean age of 48.6 ± 16.9 years. The original sample of acute coughers was significantly older on average (t60 = 3.67; p < 0.001) than those in the second sample, with a mean age of 52.3 ± 14.5 years (median age, 49.3 years; age range, 19.3 to 83.9 years) vs 38.8 ± 14.4 years (median age, 35.1 years; age range, 18.6 to 87.8 years),
Discussion
The 28-item CQLQ was designed to evaluate for the major meaningful psychosocial and physical complaints of cough. Based on extensive psychometric testing that has been previously performed and reported, the CQLQ has been shown to have dimensionality that is consistent with a cough-specific quality-of-life instrument, and to be a valid and reliable method by which to assess the impact of cough on the HRQOL of patients with both AC and CC from a variety of causes.5
Utilizing the CQLQ, we first
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Cited by (59)
Risk Factors for Persistent Chronic Cough During Consecutive Years: A Retrospective Database Analysis
2022, Journal of Allergy and Clinical Immunology: In PracticeGlobal Physiology and Pathophysiology of Cough: Part 2. Demographic and Clinical Considerations: CHEST Expert Panel Report
2021, ChestCitation Excerpt :Another explanation as to why women more frequently than men complain of chronic cough relates to the observations that the health-related quality of life of women is more adversely affected than men because women are more likely to seek medical attention because they are more apt to experience physical complaints associated with coughing, such as urinary stress incontinence, that then provoke psychosocial issues such as embarrassment.44 Similar sex differences in health-related quality of life have not been seen during acute cough.45 Various clinical conditions can affect cough efficacy and although glottic closure enhances the compressive phase of coughing, it is not essential for an effective cough.46-48
Patient-Reported Burden of Chronic Cough in a Managed Care Organization
2021, Journal of Allergy and Clinical Immunology: In PracticeCitation Excerpt :Prior studies noted that, compared with men, women exhibited an 8.7-point higher HARQ score than men,24 which was somewhat higher than the difference of 4.7 in the HARQ score found in the present study. Similar to the higher 7.8-point difference in CQLQ between women and men in the present study, significant differences of 6.1-7.426,40,41 were reported previously in smaller cohorts. In support of the greater disease burden of CC in women, capsaicin sensitivity42 and cough frequency and heightened cough reflex39 were reported to be greater in women than men.
Characteristics of Chinese chronic cough patients
2019, Pulmonary Pharmacology and TherapeuticsCitation Excerpt :In Shanghai, there is almost two-fold greater number of females than males attending with chronic cough, though their average age (45 years) is similar to patients in other regions [27–29] (Table 2). A higher cough reflex sensitivity in females [5,24,30], especially in those post-menopausal females [25], as well as a more adversely affected health-related quality of life in women with chronic cough than men have been reported in Western countries [31,32], which to some extent explains the older female predominant feature in these countries. In China, females also have an enhanced cough reflex sensitivity than males in both healthy subjects and patients with chronic cough [33].
Presented and published in part in abstract form at the annual meeting of the American Thoracic Society, May 21, 2002, Atlanta, GA.
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