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Clinical Investigations: Xercise/ClerodermaExercise Training Decreases Dyspnea and the Distress and Anxiety Associated With It: Monitoring Alone May Be as Effective as Coaching
Section snippets
Patients
The protocol was approved by the University of California, San Francisco Committee on Human Research. Patients were eligible for the study if they had moderate to severe COPD (FEV1 <60% of predicted and FEV1/FVC ratio <0.6 after inhaling 3 puffs of albuterol) resulting in dyspnea that limited their ADL, did not require continuous oxygen, were in medically stable condition, and could walk on the treadmill. Patients who had been enrolled in formal pulmonary rehabilitation (including maintenance
Sample
A total of 313 volunteers were interviewed for participation in this study. Of these, 223 were excluded before exercise testing because they either did not meet the inclusion criteria, lived too far from the medical center, or were not interested in participating. Of the 90 patients who completed screening tests, 32 failed to meet the inclusion criteria. Eight of the remaining 58 patients failed to complete the study: 4 because of hospitalization, 2 because of failure to keep appointments, 1
Discussion
The major finding of this study was that dyspnea intensity, and the distress and anxiety associated with it, decreased significantly in relationship to work performed on the treadmill after 12 supervised treadmill exercise training sessions. In addition, improvement in dyspnea with the 6-min walk test was sustained during an 8-week home walking phase and was accompanied by significant improvement in dyspnea with ADL and in self-efficacy for walking at home. These improvements in dyspnea were no
Acknowledgments
The authors express their appreciation of Richard Casaburi, MD, for help with analysis of the V-slopes.
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This research study was funded by NIH-NCNR grant RO1 NR02131.