Chest
Clinical Investigations: Home CarePredictors of Survival in Patients Receiving Domiciliary Oxygen Therapy or Mechanical Ventilation: A 10-Year Analysis of ANTADIR Observatory
Section snippets
Collection of Information
The organization of the ANTADIR has been described elsewhere and will be presented only briefly.3 Information concerning the patient's characteristics are taken from the Social Security form that is filled in by the prescribing physician. Precise prescription rules exist in France only for oxygen therapy. This treatment is reimbursed if PaO2 under room air is 55 mm Hg (7.3 kPa) or lower at two measurements in a steady state. The minimum interval between the two measurements should be at least 2
Characteristics of the Population
The characteristics of the 26,140 patients included in the study are shown in Table 1. This shows the relative amount of PMV (via a tracheostomy or a nasal or oral mask) and oxygen therapy in each diagnostic group.
Nearly all patients with obstructive lung disease receive LTOT, while PMV largely predominates in patients with neuromuscular diseases. Oxygen therapy is also preferentially prescribed in pneumoconiosis, fibrosis, and mixed lung diseases. Table 2 shows lung function parameters, ABG
Discussion
The organization of ANTADIR Observatory gives us a unique opportunity to examine the long-term evolution of more than 25,000 patients treated at home for CRI. This population represents an important proportion of patients with CRI receiving domiciliary treatment in France over the same period. The information provided from this study differs from those of the Nocturnal Oxygen Therapy Trial and Medical Research Council (MRC) studies.1, 2 It is likely that many of our patients would have been
ACKNOWLEDGMENTS
The authors wish to thank all the Participating associations: AIR, Angers; AVD, Angoulême; DON DU SOUFFLE, Besançon; AVAD, Bordeaux; AIR, Caen; AIRRA, Clermont-Ferrand; ALIZE DE BOURGOGNE, Dijon; AGIR, Grenoble; GHAHR, Le Havre; AVAD, Lille; ALAIR, Limoges; ARARD, Marseille; APARD, Montpellier; AIR, Mulhouse; ARAIRLOR, Nancy; ARIRPLO, Nantes; CARDIF, Paris; ARAI-RCHAR, Reims; AADAIRC, Rochefort; ADIR, Rouen; ADIRAL, Strasbourg; BAARD, Toulouse; SADIR, Toulouse; and ARAIR CENTRE, Tours.
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revision accepted October 5.