Chest
Clinical Investigations: Sleep/AirwaysPulmonary Hemodynamics in the Obstructive Sleep Apnea Syndrome: Results in 220 Consecutive Patients
Section snippets
METHODS
The study included consecutive, unselected patients who had been referred to the sleep laboratory for symptoms evocative of OSAS. All the patients had an established diagnosis of OSAS on the basis of polysomnographic criteria of more than 20 apneas and (or) hypopneas per hour of sleep, of which more than 80% were of the obstructive type. All the patients underwent conventional spirography and arterial blood gas measurements. All the patients included in the present study gave an informed
RESULTS
Patients were subdivided into two groups according to the results of pulmonary hemodynamic investigations. Group 1 included 37 patients with PH defined by a resting PAP of 20 mm Hg or greater. Group 2 included the remaining 183 patients without PH. It can be seen from Table 1 that the proportion of female patients was low (<10%) in both groups and that age was similar in patients with and without PH. The body mass index (BMI) was higher in PH patients (p<0.0l). Obesity defined by a BMI greater
DISCUSSION
The present study shows that 17% of OSAS patients exhibit permanent (daytime) PH, defined by a PAP of 20 mm Hg or more. Thus, resting PH is not a common finding and this figure (17%) is in good agreement with data obtained in earlier studies from our laboratory,4, 5 where the numbers of patients were smaller, 9 of 46 (20%)4 and 19 of 100 (19%),5 but also with the results of Podszus et al13 who noticed that 13 of 65 patients (20%) had PH. Higher figures of PH have been observed in earlier reports
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