Chest
Selected ReportsCytomegalovirus Pneumonitis: An Unusual Cause of Pulmonary Nodules in a Patient With AIDS
Section snippets
CASE REPORT
A 35-year-old man presented to the AIDS Clinic at the University of California, San Francisco, in August 1991, complaining of fever, malaise, fatigue, abdominal pain and a hoarse voice for the preceding two weeks. In 1987, a serologic test for HIV infection was positive and CD4 + T-lymphocyte count was 160 cells/mm3. Zidovudine and aerosolized pentamidine were prescribed. Kaposi's sarcoma developed in June 1990 but required no therapy. Non-Hodgkin's lymphoma was diagnosed by biopsy of an
DISCUSSION
The differential diagnosis of nodular lung disease in patients with AIDS is extensive and includes tuberculosis, P carinii infection, cryptococcosis, Kaposi's sarcoma and non-Hodgkin's lymphoma. When CMV pneumonitis has been described in AIDS patients, the radiographic appearance has been that of diffuse bilateral interstitial infiltrates.3 To our knowledge, no case of nodular lung disease caused by CMV infection has been reported.
Clinically significant CMV pneumonitis responsive to antiviral
ACKNOWLEDGMENT
The authors thank Nadine Lurie for editorial assistance.
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Cited by (15)
Pulmonary Nodules in Lung Transplant Recipients: Etiology and Outcome
2004, ChestCitation Excerpt :Schulman et al4 showed that in the 15 of 159 LT recipients who acquired PNs after 11 months of follow-up, Aspergillus and mycobacterial infections, as well as PTLD, accounted for 80% of PNs. There were also reports of nodular opacities following FB and TBBX due to focal hematomas,10 multiple rib fractures that mimicked PNs,11 and rare causes such as pulmonary tuberculosis,12 CMV pneumonitis,13 BO organizing pneumonia,14 and recurrent sarcoidosis.15 To date, our study of 23 LT recipients with PNs represents the largest series.
Cytomegalovirus pneumonia mimicking lung cancer in an immunocompetent host
2003, Mayo Clinic ProceedingsCitation Excerpt :The appearance of CMV pneumonia on CT in patients with AIDS has been similar to that described for other immunocompromised patients.9 In addition, single or multiple nodules measuring between 1 and 3 cm have been associated with CMV pneumonia occurring in patients with AIDS.8,14,15 In one patient, a single thick-walled cavitary lesion was described.9
Infections in HIV-infected patients with malignancy
1996, Infectious Disease Clinics of North AmericaHuman cytomegalovirus pathogenesis: an overview
1995, La Revue de medecine interneLes pneumonies à cytomégalovirus
1995, Annales de l'Institut Pasteur/Actualites