Chest
Global MedicineAllergic Bronchopulmonary Aspergillosis
Section snippets
Epidemiology of ABPA
Aspergillus hypersensitivity (AH) is defined by the presence of an immediate-type cutaneous hypersensitivity to A fumigatus antigens, and it is the first step in the development of ABPA.24 Only a minority of patients with AH develop the complete clinical picture of ABPA.25 The population prevalence of ABPA in asthma, generally referred to as 1 to 2%,5, 13, 26, 27 is based on the inference of only three studies (one peer-reviewed and two non-peer-reviewed studies).28, 29 In the only
Conclusions
A high index of suspicion for ABPA should be maintained while managing any patient with bronchial asthma whatever the severity or the level of control. Host immunologic responses are central to the pathogenesis, and they are the primary determinants of the clinical, biologic, pathologic, and radiologic features of this disorder. ABPA may precede the clinical recognition of the disorder for many years or even decades, and it is often misdiagnosed as a variety of pulmonary diseases. Because a
Acknowledgment
The author wishes to thank Dr. Amanjit Bal, Assistant Professor, Department of Histopathology, PGIMER, Chandigarh for providing the histopathology photographs.
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The author has no conflicts of interest to disclose.
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