Chest
Original Research: Sleep MedicineObstructive Sleep Apnea Syndrome Is Associated With Some Components of Metabolic Syndrome
Section snippets
Subjects
From April 2002 to March 2006, 1,205 consecutive male patients with clinical symptoms of sleep apnea were examined by polysomnography and classified into two groups by their apnea-hypopnea index (AHI) [AHI ≥ 5/h, n = 1,153; AHI < 5/h, n = 52]. Presenting symptoms were either snoring or daytime sleepiness or both. The subjects were all Japanese.
The diagnostic criteria for metabolic syndrome in Japan16 include a VFA ≥ 100 cm2. First, we selected patients with a body mass index (BMI) ≤ 30 kg/m2
Results
Table 1 summarizes the characteristics of the subjects. Two patients each in both groups were receiving antihypertensive drugs. Three patients in the OSAS group and two patients in the non-OSAS group had diabetes; of them, two patients in the OSAS group and one patient in the non-OSAS group were receiving an oral hypoglycemic agent, while the others were receiving diet therapy.
Systolic BP was higher in the OSAS group, while diastolic BP did not differ between the two groups. However, the
Discussion
This cross-sectional analysis involved a selected group of male patients with and without OSAS matched for age, BMI, and VFA. Since they were matched for abdominal obesity, we compared them for the other components of metabolic syndrome. The main finding of this study was that 19% of the men with OSAS, compared with only 4% of those without it, had at least two of the following: hypertension, hyperglycemia, and dyslipidemia. It is possible that even in nonobese OSAS subjects might be
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The authors have no conflicts of interest to disclose.
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