Vascular endothelial growth factor in patients with acute asthma
Section snippets
To the Editor:
Bronchial asthma is a chronic inflammatory disease of the airways that is characterized by airway remodeling. The histologic characteristics of chronic inflammation include angiogenesis, increased connective tissue deposition, and cellular proliferation of myofibroblasts.1 There is an increase in vessel area in bronchial asthma.2 Vascular endothelial growth factor (VEGF; vascular permeability factor) is one of the most potent proangiogenic cytokines, and it plays a central role in mediating the
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