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The AM and FM of calcium signalling

Nature volume 386, pages 759–760 (1997)Cite this article

Cells respond to external signals by transducing the information into internal messengers such as Ca2+. The information-processing capability of the Ca2+ signalling system is enhanced by the well-known engineering principles of amplitude and frequency modulation.

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References

  1. Rapp, P. E. & Berridge, M. J. J. Exp. Biol. 93, 119–132 (1981).

    CAS  Google Scholar 

  2. Dolmetsch, R. E., Lewis, R. S., Goodnow, C. C. & Healy, J. I. Nature 386, 855–858 (1997).

    Article  ADS  CAS  Google Scholar 

  3. Healy, J. I. et al. Immunity 6, 419–428 (1997).

    Article  CAS  Google Scholar 

  4. Woods, N. M., Cuthbertson, K. S. R. & Cobbold, P. H. Nature 319, 600–602 (1986).

    Article  ADS  CAS  Google Scholar 

  5. Gu, X. & Spitzer, N. C. Nature 375, 784–787 (1995).

    Article  ADS  CAS  Google Scholar 

  6. Berridge, M. J. J. Physiol. (Lond.) 499, 291–306 (1997).

    Article  CAS  Google Scholar 

  7. Bootman, M. D., Niggli, E., Berridge, M. J. & Lipp, P. J. Physiol. (Lond.) 499, 307–314 (1997).

    Article  CAS  Google Scholar 

  8. Hardingham, G. E., Chawla, S., Johnson, C. M. & Bading, H. Nature 385, 260–265 (1997).

    Article  ADS  CAS  Google Scholar 

  9. Nelson, M. T. et al. Science 270, 633–637 (1995).

    Article  ADS  CAS  Google Scholar 

  10. Tse, F. W., Tse, A., Hille, B., Horstmann, H. & Almers, W. Neuron 18, 121–132 (1997).

    Article  CAS  Google Scholar 

  11. Hajnoczky, G., Robb-Gaspers, L. D., Seitz, M. B. & Thomas, A. P. Cell 82, 415–424 (1995).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Babraham Institute Laboratory of Molecular Signalling, PO Box 158, Cambridge, CB2 3ES, UK

    Michael J. Berridge

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  1. Michael J. Berridge
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Berridge, M. The AM and FM of calcium signalling. Nature 386, 759–760 (1997). https://doi.org/10.1038/386759a0

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