Registry report
The Registry Of The International Society For Heart And Lung Transplantation: Nineteenth Official Report—2002

https://doi.org/10.1016/S1053-2498(02)00498-9Get rights and content

Introduction

The Registry of the International Society for Heart and Lung Transplantation is pleased to present its nineteenth annual report. Although the overall structure of this report is similar to that of previous reports, some important differences are worth noting: First, the entire Registry includes data for such a large group of recipients (61,533 heart transplants, 2,935 heart–lung transplants, 14,588 lung transplants) that any recent changes in the most recent cohort of patients can easily be diluted by the large number of previous recipients. Thus, for many of the analyses we have included only individuals undergoing transplantation in a recent time period. Second, we now present data regarding several post-transplant complications, including malignancies and chronic rejection, in a Kaplan–Meier format to better illustrate the cumulative incidence of these problems over the lifetime of the recipient. Finally, we have expanded the scope of reporting of immunosuppressive medication management to include the use of “induction” immunosuppression, and to begin to describe the use of specific combinations of medications. As has been the case in the past, the entire set of figures and tables from this report, as well as additional information not included here, is available without charge at the ISHLT website (www.ishlt.org).

Section snippets

Transplant volume and indications

As has been the case for the past several years, the number of reported heart transplants continues to decline (Figure 1). This is almost entirely due to a decrease in transplants reported by non-U.S. centers; whether this decline is due to an actual decrease in the numbers of transplants or simply a decrease in reporting is unknown. The age distribution of heart transplant recipients has changed somewhat in recent years (Figure 2); the most notable changes are a decrease in the proportion of

Transplant volume and indications

After a period of rapid growth during the early 1990s, the yearly number of lung transplants increased only slightly in the latter half of the decade (Figure 17). Since 1995, lung transplant operations have been relatively equally divided between unilateral and bilateral procedures, and about 67% of lung recipients have been reported from U.S. centers.

The leading indications for lung transplants performed between 1995 and 2001 were chronic obstructive pulmonary disease (COPD, 39.4%),

Transplant volume and indications

Although reporting for 2001 may not be complete, the decline in activity in heart–lung transplantation that began in 1990 appears to have continued (Figure 27). Through 2000, this downward trend in reported activity had occurred primarily in the non-U.S. centers. In addition to the decreasing total transplant volume, the number of centers reporting heart–lung transplants has decreased worldwide. Approximately 10% to 25% of heart–lung transplants have been performed for recipients <18 years of

Acknowledgements

The authors acknowledge the following contributors, without whose diligent efforts the continued operation and quality of the Registry would not be possible: Amanda Rowe (ISHLT Executive Director); George Beasley, Denise Wise and Kelly Balagtas (UNOS Transplant Information Institute); and staff members of all of the many participating transplant centers, organ procurement organizations and organ exchange organizations around the world.

First page preview

First page preview
Click to open first page preview

References (0)

Cited by (314)

  • Interventional Radiological Treatment of Orthotopic Heart Transplant Complications

    2023, Techniques in Vascular and Interventional Radiology
View all citing articles on Scopus
View full text