Elsevier

Environment International

Volume 24, Issue 7, October 1998, Pages 703-712
Environment International

Critical aspects on the significance of microbial volatile metabolites as indoor air pollutants

https://doi.org/10.1016/S0160-4120(98)00065-8Get rights and content

Abstract

The effect of microbial growth in building materials on airborne levels of volatile organic compounds (VOCs) was demonstrated by theoretically calculating indoor air concentrations of selected VOCs for rooms with and without microbial contamination. The recommended indoor air level for individual VOCs was also estimated on the basis of their sensory irritation potency. Furthermore, the irritation potency for the mixtures of certain compounds (microbial volatile metabolites, MVOCs) at airborne concentrations measured in problem buildings was evaluated. The theoretical airborne concentrations of certain compounds, which are generally regarded as MVOCs, were estimated to be only about 1% higher in the biocontaminated rooms than in those with moist sterile materials. In fact, no individual VOCs indicated exclusively microbial contamination, but they could also be emitted even from sterile, moist constructions. Exposure to mixtures of the selected non-reactive VOCs at the theoretical airborne concentrations would not result in sensory irritation in humans, and, thus, microbial growth in constructions should not increase the probability of irritating symptoms considerably. The data on MVOC concentrations measured in some problem buildings also supported this idea. Irritation would be expected when the airborne concentrations of single non-reactive compounds approach a level of hundreds of μg/m3 or mg/m3.

References (49)

  • K. Andersson

    TVOC and health in non-industrial indoor environments

  • ASTM (American Society for Testing and Materials)

    Standard test method for estimating sensory irritancy of airborne chemicals

    (1984)
  • D.R. Berry

    Products of primary metabolic pathways

  • J. Bjurman et al.

    Growth-phase-related production of potential volatile organic tracer compounds by moulds on wood

    Indoor Air

    (1997)
  • T. Börjesson et al.

    Analysis of volatile compounds for detection of molds in stored cereals

    Cereal Chem.

    (1989)
  • T. Börjesson et al.

    Volatile metabolites and other indicators of Penicillium aurantiogriseum growth on different substrates

    Appl. Environ. Microbiol.

    (1990)
  • T.S. Börjesson et al.

    Off-odorous compounds produced by molds on oatmeal agar: Identification and relation to other growth characteristics

    J. Agric. Food Chem.

    (1993)
  • S.K. Brown et al.

    Concentrations of volatile organic compounds in indoor air — A review

    Indoor Air

    (1994)
  • C.P. Dionigi et al.

    Effect of temperature and oxygen concentration on geosmin production by Streptomyces tendae and Penicillium expansum

    J. Agric. Food Chem.

    (1994)
  • ECA-IAQ (European Collaborative Action, Indoor Air Quality & Its Impact on Man)

    Evaluation of VOC emissions from building products

  • F. Englund et al.

    Indoor air VOC levels during the first year of a new three-story building with wooden frame

  • H.H. Jelen et al.

    Production of volatile sesquiterpenes by Fusarium sambucinum strains with different abilities to synthesize trichothecenes

    Appl. Environ. Microbiol.

    (1995)
  • E. Kaminski et al.

    Identification of the predominant volatile compounds produced by Aspergillus flavus

    Appl. Microbiol.

    (1972)
  • E. Kaminski et al.

    Volatile flavor compounds produced by molds of Aspergillus, Penicillium and Fungi imperfecti

    Appl. Microbiol.

    (1974)
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