Randomized, double-blind, controlled trial of long-term diuretic therapy for bronchopulmonary dysplasia*
References (18)
- et al.
Short and long-term effects of furosemide on lung function in infants with bronchopulmonary dysplasia
J Pediatr
(1986) - et al.
Furosemide acutely decreases airways resistance in chronic bronchopulmonary dysplasia
Pediatrics
(1983) - et al.
Renal function and diuretic therapy in infants and children. II
J Pediatr
(1975) - et al.
The management of bronchopulmonary dysplasia
Clin Perinatol
(1987) - et al.
Mineral excretion in premature infants receiving various diuretic therapies
J Pediatr
(1988) - et al.
Pathogenesis of bronchopulmonary dysplasia following hyaline membrane disease
Am J Pathol
(1976) - et al.
Controlled trial of furosemide therapy in infants with chronic lung disease
J Pediatr
(1985) - et al.
Pulmonary and renal responses to furosemide in infants with stage III–IV bronchopulmonary dysplasia
Am J Dis Child
(1985) - et al.
Effect of oral diuretics on pulmonary mechanics in infants with chronic bronchopulmonary dysplasia: results of a double-blind cross-over sequential trial
Pediatrics
(1984)
Cited by (64)
Neonatal Diuretic Therapy: Furosemide, Thiazides, and Spironolactone
2012, Clinics in PerinatologyCitation Excerpt :Diuretic therapy was also associated with increased urine output and potassium and phosphorus excretion. In a randomized, double-blind, controlled trial on long-term diuretic therapy on ventilated infants requiring 30% or more Fio2 and greater than 30 days of age, Albersheim and colleagues52 reported no statistical difference in hospital or ventilator days in infants receiving hydrochlorothiazide and spironolactone. After 4 weeks of therapy, respiratory compliance was significantly higher in the treatment compared with control group.
Adjunctive pharmacotherapy in neonates with respiratory failure
2009, Seminars in Fetal and Neonatal MedicineCitation Excerpt :Thiazides used in combination with spironolactone have been evaluated in a number of randomised trials. Administration of the combination for 1–4 weeks to very low birth weight (VLBW) preterm infants with moderate BPD has resulted in increased urine output and improvements in oxygenation and pulmonary compliance, and reduction in airway resistance,34,38–41 or even improved survival at discharge.40 A systematic review on the use of thiazides in BPD infants showed that long-term administration of thiazides improved lung compliance after 4 weeks and reduced administration of furosemide, regardless of the need for mechanical ventilation at the onset of treatment.
Chronic Respiratory Complications of Prematurity
2008, Pediatric Respiratory MedicineDiuretics use in the management of bronchopulmonary dysplasia in preterm infants: A systematic review
2024, Acta Paediatrica, International Journal of PaediatricsBronchopulmonary Dysplasia
2023, Fetal and Neonatal Pharmacology for the Advanced Practice NurseSummary for Clinicians: Clinical Practice Guidelines for Outpatient Respiratory Management of Infants, Children, and Adolescents with Post-Prematurity Respiratory Disease
2022, Annals of the American Thoracic Society
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Supported by a grant from the Vancouver Foundation (British Columbia Medical Services Foundation 85-37). These findings were presented at the Society for Pediatric Research, Washington, D.C., May 5, 1988.