Original contributionHypoxia increases production of interleukin-1 and tumor necrosis factor by human mononuclear cells
References (45)
- et al.
Phorbol myristate acetate stimulates LAF production by the macrophage cell line P388D1
Cell Immunol
(1978) - et al.
Prostaglandin E2 regulates macrophage-derived tumor necrosis factor gene expression
J Biol Chem
(1988) - et al.
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
Anal Biochem
(1983) Biology of interleukin 1
FASEB J
(1988)- et al.
Cachectin: more than a tumor necrosis factor
N Engl J Med
(1987) - et al.
Shock and tissue injury induced by recombinant human cachectin
Science
(1986) - et al.
Recombinant interleukin-1 and recombinant tumor necrosis factor synergize in vivo to induce early endotoxin tolerance and associated hematopoietic changes
Infect Immun
(1988) - et al.
C5a induction of human interleukin 1
- et al.
C5a stimulates secretion of tumor necrosis factor from human momonuclear cells in vitro
J Exp Med
(1988) - et al.
Interleukin-1 induces interleukin-1 III. Specific inhibition of interleukin-1 production by gamma-interferon
J Immunol
(1988)
Glucocorticoids selectively inhibit the transcription of the interleukin 1 gene and decrease the stability of interleukin 1 mRNA
Prostaglandins posttranscriptionally inhibit monocyte expression of interleukin 1 activity by increasing intracellular cyclic adenosine monophosphate
J Immunol
In vitro production of IL-1β, IL-1α, TNF and IL-2 in healthy subjects: Distribution, effect of cyclooxygenase inhibition, and evidence of independent gene regulation
Eur J Immunol
Interleukin 1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear leukocytes, monocytes, and related leukocyte cell lines
J Clin Invest
Neutrophil activation on biological surfaces
Interleukin-1-induced granulocytopenia and pulmonary leukostasis in rabbits
J Appl Physiol
Direct evidence for granuloma-inducing activity of interleukin-1
Am J Pathol
Recombinant tumor necrosis factor/cachectin and interleukin 1 pretreatment decreases lung oxidized glutathione accumulation, lung injury, and mortality in rats exposed to hyperoxia
J Clin Invest
Hypoxia increases glutathione redox cycle and protects rat lungs against oxidants
J Appl Physiol
Structural and biochemical adaptive changes in rat lungs after exposure to hypoxia
Lab Invest
Protection from O2 toxicity by preexposure to hypoxia: Lung antioxidant enzyme role
J Appl Physiol
Protection from oxygen toxicity with endotoxin: Role of the endogenous antioxidant enzymes of the lung
J Clin Invest
Cited by (218)
The effects of N-Acetylcysteine on serum level of inflammatory biomarkers in adults. Findings from a systematic review and meta-analysis of randomized clinical trials
2020, CytokineCitation Excerpt :The mechanism by which NAC reduces inflammatory biomarkers among CKD patients remained to be elucidated, but some explanations may justify this observation. CKD can augment the depletion of glutathione and thiols which have antioxidant properties [68]; this can reduce the ability of intrinsic antioxidants to fight with free radicals and subsequent inflammation [69]. So, NAC has been proposed to replenish glutathione reservoir and improve inflammatory biomarkers [68].
Keep an eye on adenosine: Its role in retinal inflammation
2020, Pharmacology and TherapeuticsModulation of megakaryopoiesis and platelet production during inflammation
2019, Thrombosis ResearchCerebral White Matter Injury: Pathogenesis
2018, Volpe's Neurology of the NewbornPathophysiology
2018, Volpe's Neurology of the NewbornShaping the niche in macrophages: Genetic diversity of the M. tuberculosis complex and its consequences for the infected host
2018, International Journal of Medical MicrobiologyCitation Excerpt :However, also other factors such as small lipid mediators (Chen et al., 2008; Divangahi et al., 2013; Mayer-Barber et al., 2014) and other tissue derived differentiation factors (such as Macrophage-Colony Stimulating Factor (M-CSF) and Granulocyte-Macrophage-Colony Stimulating Factor (GM-CSF), Wingless-Type MMTV Integration Site Family, Member (WNT) proteins, and others) significantly impact macrophage differentiation and function (Brandenburg and Reiling, 2016; Martinez and Gordon, 2014). The immunological response and cellular differentiation further depend on local oxygen availability, as it has been shown that limited oxygen tension leads to an enhanced inflammatory and antimycobacterial activity (Ghezzi et al., 1991; Lewis et al., 1999; Meylan et al., 1992; Scannell et al., 1993). Recently, it became evident that cellular effector functions are tightly interlinked with selected metabolic pathways as TB infection experiments with human macrophages have shown that the antimicrobial activity of these cells is directly linked to glycolysis (Gleeson et al., 2016).