Brief communication
Activation of lavage lymphocytes in lung injuries caused by radiotherapy for lung cancer

https://doi.org/10.1016/0360-3016(95)02101-9Get rights and content

First page preview

First page preview
Click to open first page preview

References (45)

  • S.A. Brod et al.

    T-T cell interactions are mediated by adhesion molecules

    Eur. J. Immunol.

    (1990)
  • B.J. Brooks et al.

    Pulmonary toxicity with combined modality therapy for limited small cell lung cancer

    J. Clin. Oncol.

    (1986)
  • T.L. Chevalier et al.

    Radiation alone vs. combined chemotherapy and radiotherapy in nonresectable nonsmall-cell lung cancer: First analysis of a randomized trial in 353 patients

    J. Natl. Cancer. Inst.

    (1991)
  • J.E. Coggle et al.

    Radiation effects in the lung

    Environ. Health Perspect.

    (1986)
  • J.F. Cordier et al.

    Bronchoalveolar lavage in radiation pneumonitis

    Bull. Eur. Physiopathol. Respir.

    (1984)
  • R.O. Dillman et al.

    A randomized trial of induction chemothrapy plus high-dose radiation vs. radiation alone in stage II non-small-cell lung cancer

    N. Engl. J. Med.

    (1990)
  • L.F. Fajardo et al.

    Radiation injury in surgical pathology

    Am. J. Surg. Pathol.

    (1978)
  • J.A. Fleming et al.

    Sequelae to radical irradiation in carcinoma of the breast

    Br. J. Radiol.

    (1961)
  • K. Fukudome et al.

    Strong induction of ICAM-1 in human T cells transformed by human T-cell-leukemia virsus type 1 and depression of ICAM-1 or LFA-1 in adult T-cell-leukemia-derived cell lines

    Int. J. Cancer

    (1992)
  • P.G. Gibson et al.

    Radiaiton-induced lung injury: A hypersensitivity pneumonitis?

    Ann. Intern. Med.

    (1988)
  • N.J. Gross

    Pulmonary effects of radiation therapy

    Ann. Intern. Med.

    (1977)
  • H.H. Hansen et al.

    Intensive combined chemotherapy and radiotherapy in patients with nonresectable bronchogenic carcinoma

    Cancer

    (1972)
  • Cited by (61)

    • Association of T Cell Senescence with Radiation Pneumonitis in Patients with Non-small Cell Lung Cancer

      2023, International Journal of Radiation Oncology Biology Physics
      Citation Excerpt :

      During this acute inflammatory phase, vascular permeability increases and diverse lymphocyte populations recruit to the site of inflammation.38 Previous studies have demonstrated association between increase in CD4+ and CD8+ T cells in the bronchoalveolar lavage after irradiation and development of pneumonitis.41,42 In infectious lung diseases, CD8+ T cells have also been shown to contribute to lung injury due to their cytotoxic effects via production of pro-inflammatory cytokines and cytotoxic granules.43

    • Single nucleotide polymorphisms in CBLB, a regulator of T-cell response, predict radiation pneumonitis and outcomes after definitive radiotherapy for non-small-cell lung cancer

      2016, Clinical Lung Cancer
      Citation Excerpt :

      Accumulating evidence has suggested a close relationship between radiotherapy and the immune system. The immune system affects both the risk of developing cancer and the risk of recurrence,3 and contributes to tumor treatment response and toxic effects after ionizing radiation.4-6 These studies suggest that immune activation plays a significant role in tumor control by radiotherapy and that important immune regulatory genes could be used to predict outcomes after radiotherapy.

    View all citing articles on Scopus

    This manuscript was presented at the 7th World Conference Lung Cancer, June 26 to July 1, 1994, in Colorado Springs, Co.

    View full text