Original articleLevels of IgE in serum from normal children and allergic children as measured by an enzyme immunoassay
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2000, ChestCitation Excerpt :This small differ- ence in age is unlikely to affect our major findings. While serum IgE increases with age, IgE levels do not increase by twofold in a year.30 Others have reported that children become less responsive to methacholine as they become older.31,32