Abstract
Objective
This study represents the experience of a tertiary care center in Saudi Arabia on non-cystic fibrosis bronchiectasis.
Methods
A retrospective review of all patients with confirmed Non-Cystic Fibrosis (Non-CF) bronchiectasis by chest X-ray and or CT chest in a pulmonary clinic for the period 1993–2005 at a tertiary care center in Riyadh.
Results
A total of 151 cases were diagnosed as Non-CF bronchiectasis. Siventy-five (49.7%) were males, 76(50.3%) were females. One hundred forty-eight (98%) are alive and 3(2%) died. The southwestern regions constituted 72(50%) of the cases. There is a period (5±3.2) years between the start of symptoms and the diagnosis of bronchiectasis. More than 2/3 of the patients had cough, tachypnea, wheezing, sputum production and failure to thrive. Ninety one (60%) had associated disease: Pulmonary diseases in 48(32%), immunodefficiency in 27(18%), CNS in 18(12%), cardiac in 12(8%), and asthma in 103(68%) of the patients. Left lower lobes were commonly involved in 114(76%) cases. Sixty-eight (67%) were found to have sinusitis. Forty-nine (32%) developed gastroesophgeal reflux (GER). Hemophilus influenza was cultured in 56(37%), Strept pneumoniae in 25(17%), and Pseudomonas aeruginosa in 24(16%) of the patients. 80% of the patients who had pulmonary function test had abnormal changes. Disease progression was related to development of symptoms before 5 years of age, persistent atelectasis, and right lower lobe involvement (p < 0.05).
Conclusion
Non-CF bronchiectasis is a common problem in Saudi Arabia. Early recognition and institution of treatment with proper vaccination of available anti-bacterial and anti-viral vaccines are encouraged to prevent progression of the disease.
Similar content being viewed by others
References
Callahan CW, Redding G. Bronchiectasis in children: Orphan disease or persistent problem? Pediatr Pulmonol 2002; 33: 492–496.
Karakoc GB, Yilmaz M, Altintas DU, Kendiri SG. Bronchiectasis: Still a problem. Pediatr Pulmonol 2001; 32: 175–178.
Brown MA, Leman RJ. Bronchiectasis. In Chernick V, Boat T, eds. Kendig’s disorder of the respiratory tract in children. 6th edition, Philadelphia; WB Saunders; 1998. 538–560.
Biering A. Childhood pneumonia, including pertussis, pneumonia and bronchiectasis: a follow-up study of 151 patients. Acta Pediatr 1956; 45: 348–351.
Ruberman W, Shaufer I, and Bioondo T. Bronchiectasis and acute pneumonia. Am Rev Tuber 1957; 76: 761–765.
Field CE. Bronchiectasis: Third report on a follow-up study of medical and surgical cases from childhood. Arch Dis Child 1969; 44: 551–555
Dawson K.P., Bakalinova D. Child bronchiectasis in a desert location. Middle East Pediatrics 1996; 1: 6–8
Singleton R, Morris A, Redding G, Poll J, Hock P, Martinez P, Kruse D, Bulkow LR, Peterson KM, Lewis C. Bronchiectasis in Alaska Native children: causes and clinical courses. Pediatr Pulmonol 2000; 29: 182–187.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Banjar, H.H. Clinical profile of Saudi children with bronchiectasis. Indian J Pediatr 74, 149–152 (2007). https://doi.org/10.1007/s12098-007-0008-z
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12098-007-0008-z