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Prospective analysis of depression and psychological distress before and after surgical resection of lung cancer

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Abstract

Objectives

The psychological effects of surgery have received little attention in patients with lung cancer, so it is unclear how much psychological support is required by these patients. This study was done to assess the mental state of patients with lung cancer before and after surgery and to determine their need for psychological care.

Methods

A group of 165 patients with lung cancer scheduled for surgical treatment were included in this study. They were asked to complete the Profile of Mood States questionnaire before surgery and on discharge after completion of treatment. The data on mood from the questionnaires were analyzed.

Results

Tension-anxiety improved significantly after surgery, whereas the fatigue score increased significantly. The scores for depression-dejection and confusion were elevated before surgery and were unchanged afterward.

Conclusions

Patients with lung cancer were depressed before surgery and remained depressed after their operations, although postoperative tension-anxiety diminished. These results indicate that lung cancer patients need psychological support to alleviate depression during the perioperative period.

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References

  1. PJ Hollen RJ Gralla MG Kris C Cox CP Belani SM Grunberg et al. (1994) ArticleTitleMeasurement of quality of life in patients with lung cancer in multicenter trials of new therapies: psychometric assessment of the Lung Cancer Symptom Scale Cancer 73 2087–98 Occurrence Handle8156514 Occurrence Handle10.1002/1097-0142(19940415)73:8<2087::AID-CNCR2820730813>3.0.CO;2-X Occurrence Handle1:STN:280:DyaK2c3gsl2lug%3D%3D

    Article  PubMed  CAS  Google Scholar 

  2. A Montazeri CR Gillis J McEwen (1998) ArticleTitleQuality of life in patients with lung cancer: a review of literature from 1970 to 1995 Chest 113 467–81 Occurrence Handle9498968 Occurrence Handle1:STN:280:DyaK1c7ktVyjuw%3D%3D

    PubMed  CAS  Google Scholar 

  3. J Dancey FA Shepherd RJ Gralla YS Kim (2004) ArticleTitleQuality of life assessment of second-line docetaxel versus best supportive care in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy: results of a prospective, randomized phase III trial Lung Cancer 43 183–94 Occurrence Handle14739039 Occurrence Handle10.1016/j.lungcan.2003.09.001

    Article  PubMed  Google Scholar 

  4. D Cella A Peterman S Hudgens K Webster MA Socinski (2003) ArticleTitleMeasuring the side effects of taxane therapy in oncology: the functional assessment of cancer therapy-taxane (FACT-taxane) Cancer 98 822–31 Occurrence Handle12910528 Occurrence Handle10.1002/cncr.11578 Occurrence Handle1:CAS:528:DC%2BD3sXntVWgurY%3D

    Article  PubMed  CAS  Google Scholar 

  5. JA Langendijk NK Aaronson JM de Jong GPM ten Velde MJ Muller RJ Lamers et al. (2001) ArticleTitleProspective study on quality of life before and after radical radiotherapy in non-small-cell lung cancer J Clin Oncol 19 2123–33 Occurrence Handle11304764 Occurrence Handle1:STN:280:DC%2BD3M3mtFOisw%3D%3D

    PubMed  CAS  Google Scholar 

  6. JA Langendijk NK Aaronson JM de Jong GPM ten Velde MJ Muller BJ Slotman et al. (2002) ArticleTitleQuality of life after curative radiotherapy in stage I non-small-cell lung cancer Int J Radiat Oncol Biol Phys 53 847–53 Occurrence Handle12095549 Occurrence Handle10.1016/S0360-3016(02)02847-X

    Article  PubMed  Google Scholar 

  7. RE Dales R Belanger FM Shamji J Leech A Crepeau HJ Sachs (1994) ArticleTitleQuality-of-life following thoracotomy for lung cancer J Clin Epidemiol 47 1443–9 Occurrence Handle7730853 Occurrence Handle10.1016/0895-4356(94)90088-4 Occurrence Handle1:STN:280:DyaK2M3kvVegug%3D%3D

    Article  PubMed  CAS  Google Scholar 

  8. CM Mangione L Goldman EJ Orav ER Marcantonio A Pedan LE Ludwig et al. (1997) ArticleTitleHealth-related quality of life after elective surgery: measurement of longitudinal changes J Gen Intern Med 12 686–97 Occurrence Handle9383137 Occurrence Handle10.1046/j.1525-1497.1997.07142.x Occurrence Handle1:STN:280:DyaK1c%2FktlCrtw%3D%3D

    Article  PubMed  CAS  Google Scholar 

  9. H Sugiura T Morikawa M Kaji Y Sasamura S Kondo H Katoh (1999) ArticleTitleLong-term benefits for the quality of life after video-assisted thoracoscopic lobectomy in patients with lung cancer Surg Laparosc Endosc Percutan Tech 9 403–8 Occurrence Handle10872623 Occurrence Handle10.1097/00019509-199912000-00007 Occurrence Handle1:STN:280:DC%2BD3czivFShtg%3D%3D

    Article  PubMed  CAS  Google Scholar 

  10. WW Li TW Lee AP Yim (2004) ArticleTitleQuality of life after lung cancer resection Thorac Surg Clin 14 353–65 Occurrence Handle15382767 Occurrence Handle10.1016/S1547-4127(04)00023-4

    Article  PubMed  Google Scholar 

  11. WW Li TW Lee SS Lam CS Ng AD Sihoe IY Wan et al. (2002) ArticleTitleQuality of life following lung cancer resection: video-assisted thoracic surgery vs thoracotomy Chest 122 584–9 Occurrence Handle12171836 Occurrence Handle10.1378/chest.122.2.584

    Article  PubMed  Google Scholar 

  12. H Yoshimura (2001) ArticleTitleQuality of life (QOL) versus curability for lung cancer surgery Ann Thorac Cardiovasc Surg 7 127–32 Occurrence Handle11481016 Occurrence Handle1:STN:280:DC%2BD3Mvjt1Gjtg%3D%3D

    PubMed  CAS  Google Scholar 

  13. C Myrdal S Valtysdottir M Lambe E Stahle (2003) ArticleTitleQuality of life following lung cancer surgery Thorax 58 194–7 Occurrence Handle12612291 Occurrence Handle10.1136/thorax.58.3.194 Occurrence Handle1:STN:280:DC%2BD3s7hs1Ggtw%3D%3D

    Article  PubMed  CAS  Google Scholar 

  14. LR Derogatis GR Morrow J Fetting D Penman S Piasetsky AM Schmale et al. (1983) ArticleTitleThe prevalence of psychiatric disorders among cancer patients JAMA 249 751–7 Occurrence Handle6823028 Occurrence Handle10.1001/jama.249.6.751 Occurrence Handle1:STN:280:DyaL3s7ht1entw%3D%3D

    Article  PubMed  CAS  Google Scholar 

  15. P Hopwood RJ Stephens (2000) ArticleTitleDepression in patients with lung cancer: Prevalence and risk factors derived from quality-of-life data J Clin Oncol 18 893–903 Occurrence Handle10673533 Occurrence Handle1:STN:280:DC%2BD3c7jvFCqtA%3D%3D

    PubMed  CAS  Google Scholar 

  16. Y Uchitomi I Mikami A Kugaya N Akizuki K Nagai Y Nishiwaki et al. (2000) ArticleTitleDepression after successful treatment for non-small cell lung carcinoma Cancer 89 1172–9 Occurrence Handle10964348 Occurrence Handle10.1002/1097-0142(20000901)89:5<1172::AID-CNCR27>3.0.CO;2-U Occurrence Handle1:STN:280:DC%2BD3cvjsVWrug%3D%3D

    Article  PubMed  CAS  Google Scholar 

  17. A Montazeri R Milroy D Hole J McEwen CR Gillis (1998) ArticleTitleAnxiety and depression in patients with lung cancer before and after diagnosis: findings from a population in Glasgow, Scotland J Epidemiol Community Health 52 203–4 Occurrence Handle9616429 Occurrence Handle1:STN:280:DyaK1c3nvFCjsw%3D%3D Occurrence Handle10.1136/jech.52.3.203

    Article  PubMed  CAS  Google Scholar 

  18. DF Cella B Orofiamma JC Holland PM Silberfarb S Tross M Feldstein et al. (1987) ArticleTitleThe relationship of psychological distress, extent of disease, and performance status in patients with lung cancer Cancer 60 1661–7 Occurrence Handle3621136 Occurrence Handle10.1002/1097-0142(19871001)60:7<1661::AID-CNCR2820600740>3.0.CO;2-4 Occurrence Handle1:STN:280:DyaL2szgtFejsA%3D%3D

    Article  PubMed  CAS  Google Scholar 

  19. H Minagawa Y Uchitomi S Yamawaki K Ishitani (1996) ArticleTitlePsychiatric morbidity in terminally ill cancer patients Cancer 78 1131–7 Occurrence Handle8780554 Occurrence Handle10.1002/(SICI)1097-0142(19960901)78:5<1131::AID-CNCR26>3.0.CO;2-2 Occurrence Handle1:STN:280:DyaK28znsValsQ%3D%3D

    Article  PubMed  CAS  Google Scholar 

  20. T Akechi H Okamura Y Nishiwaki Y Uchitomi (2001) ArticleTitlePsychiatric disorders and associated and predictive factors in patients with unresectable nonsmall cell lung carcinoma Cancer 92 2609–22 Occurrence Handle11745196 Occurrence Handle10.1002/1097-0142(20011115)92:10<2609::AID-CNCR1614>3.0.CO;2-K Occurrence Handle1:STN:280:DC%2BD3Mnps1aqsQ%3D%3D

    Article  PubMed  CAS  Google Scholar 

  21. A Kugaya T Akechi T Okuyama H Okamura Y Uchitomi (1998) ArticleTitleScreening for psychological distress in Japanese cancer patients Jpn J Clin Oncol 28 333–8 Occurrence Handle9703862 Occurrence Handle10.1093/jjco/28.5.333 Occurrence Handle1:STN:280:DyaK1czmvFCrtw%3D%3D

    Article  PubMed  CAS  Google Scholar 

  22. Y Uchitomi I Mikami K Nagai Y Nishiwaki T Akechi H Okamura (2003) ArticleTitleDepression and psychological distress in patients during the year after curative resection of non-small-cell lung cancer J Clin Oncol 21 69–77 Occurrence Handle12506173 Occurrence Handle10.1200/JCO.2003.12.139

    Article  PubMed  Google Scholar 

  23. DM McNair M Lorr LF Droppleman (1971) Profile of mood states Educational and Industrial Testing Service Sam Diego

    Google Scholar 

  24. P Hermanek LH Sobin (1992) UICC TNM classification of malignant tumors EditionNumber4th edn Springer-Verlag Berlin

    Google Scholar 

  25. NK Aaronson S Ahmedzai B Bergman M Bullinger A Cull NJ Duez et al. (1993) ArticleTitleThe European Organization for Research and Treatment of Cancer QLQ-C30; a quality of life instrument of use in international clinical trials in oncology J Natl Cancer Inst 85 365–75 Occurrence Handle8433390 Occurrence Handle10.1093/jnci/85.5.365 Occurrence Handle1:STN:280:DyaK3s7msVarsQ%3D%3D

    Article  PubMed  CAS  Google Scholar 

  26. K Eguchi M Fukutani M Kanazawa K Tajima Y Tanaka C Morioka et al. (1992) ArticleTitleFeasibility study on quality-of-life questionnaire for patients with advanced lung cancer Jpn J Clin Oncol 22 185–93 Occurrence Handle1518167 Occurrence Handle1:STN:280:DyaK38zovFCksw%3D%3D

    PubMed  CAS  Google Scholar 

  27. DF Cella DS Tulsky G Gray B Sarafian E Linn A Bonomi et al. (1993) ArticleTitleThe Functional Assessment of Cancer Therapy scale: development and validation of the general measure J Clin Oncol 11 570–9 Occurrence Handle8445433 Occurrence Handle1:STN:280:DyaK3s7oslKqsQ%3D%3D

    PubMed  CAS  Google Scholar 

  28. CM Crumlish (1994) ArticleTitleCoping and emotional response in cardiac surgery patients West J Nurs Res 16 57–68 Occurrence Handle8128669 Occurrence Handle10.1177/019394599401600105 Occurrence Handle1:STN:280:DyaK2c7nsVOksA%3D%3D

    Article  PubMed  CAS  Google Scholar 

  29. JA Brooks KA Kesler CS Johnson D Ciaccia JW Brown (2002) ArticleTitleProspective analysis of quality of life after surgical resection for esophageal cancer: preliminary results J Surg Oncol 81 185–94 Occurrence Handle12451623 Occurrence Handle10.1002/jso.10175

    Article  PubMed  Google Scholar 

  30. A Akabayashi K Yokoyama S Araki K Shimada (1991) ArticleTitleClinical applications of the Japanese edition of profile of mood states (POMS) Shinshin Igaku 31 577–82

    Google Scholar 

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Authors and Affiliations

  1. Department of General Thoracic Surgery, Juntendo University, School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan

    Shiaki Oh MD, Hideaki Miyamoto MD, PhD, Akio Yamazaki MD, PhD, Ryuta Fukai MD, Kazu Shiomi MD, Satoshi Sonobe MD, PhD, Yuichi Saito MD, Motoki Sakuraba MD, PhD, Toshiro Futagawa MD, PhD & Yukinori Sakao MD, PhD

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  1. Shiaki Oh MD
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  2. Hideaki Miyamoto MD, PhD
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  3. Akio Yamazaki MD, PhD
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  4. Ryuta Fukai MD
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  5. Kazu Shiomi MD
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  6. Satoshi Sonobe MD, PhD
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  7. Yuichi Saito MD
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  8. Motoki Sakuraba MD, PhD
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  9. Toshiro Futagawa MD, PhD
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  10. Yukinori Sakao MD, PhD
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Correspondence to Shiaki Oh MD.

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Oh, S., Miyamoto, H., Yamazaki, A. et al. Prospective analysis of depression and psychological distress before and after surgical resection of lung cancer. Gen Thorac Cardiovasc Surg 55, 119–124 (2007). https://doi.org/10.1007/s11748-006-0084-4

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  • DOI: https://doi.org/10.1007/s11748-006-0084-4

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